We investigated the effects of low lipoprotein receptor deficiency in cholesterol blood
concentrations, blood pressure, hemostatic factors, and the autonomic nervous system in …

Apolipoprotein (apoE) E is a multifunctional protein that plays a critical role in atherogenesis,
in part by regulating the intimal proliferation of vascular smooth muscle cells. Recently, a …

ApoE/LDLR–/–mice represent a reliable model of atherosclerosis. However, it is not clear
whether cardiac performance is impaired in this murine model of atherosclerosis. Here, we …

The structure of mouse atherosclerotic lesions may differ from that of humans, and mouse
atherosclerotic plaques do not rupture except in some specific locations such as the …

Peroxisome proliferator-activated receptor-γ 1 (PPAR γ 1) is an important transcription factor
involved in atherosclerosis progression. Thus, PPAR γ 1 appears to be an interesting gene …

This study investigated whether Panax notoginseng saponins (PNS) reduced atherosclerotic
lesion formation in apolipoprotein E knockout (ApoE‐KO) mice and illustrated the potential …

Atherothrombosis is a complex disease which includes two different pathologies:
atherosclerosis, the process of plaque formation in the arterial wall and thrombosis, the …

The last decade has seen a number of important advances in the use of animal models of
atherosclerosis progression. Small animal models, particularly mouse knockouts and rabbit …

Despite numerous advances made in identifying the genes for rare mendelian forms of
cardiovascular disease (CVD), relatively little is known about the common, complex forms at …