Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

The decline of the immune system appears to be an intractable consequence of aging,
leading to increased susceptibility to infections, reduced effectiveness of vaccination and …

The endocannabinoid system is known to have positive effects on depression partly through
its actions on neurotrophins, such as Brain-Derived Neurotrophic Factor (BDNF). As BDNF is …

Evidence that psychoactive substance use disorders, bulimia nervosa, pathological
gambling, and sexual addiction share an underlying biopsychological process is …

The association between cannabis use and psychosis has long been recognized. Recent
advances in knowledge about cannabinoid receptor function have renewed interest in this …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Simple Summary This review was aimed at exploring the potentiality of drugging the
endocannabinoid system as a therapeutic option for Alzheimer's disease (AD). Recent …

The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …

Huntington's disease (HD) is a neurodegenerative disease for which there is no curative
treatment available. Given that the endocannabinoid system is involved in the pathogenesis …

Over the past several decades, benzodiazepines and the newer non-benzodiazepines have
become the anxiolytic/hypnotics of choice over the more readily abused barbiturates. While …