Folate is the generic term for both naturally occurring food folate and folic acid, the fully
oxidized monoglutamate form of the vitamin that is used in dietary supplements and fortified …

Maternal nutrition during pregnancy can induce epigenetic alterations in the fetal genome,
such as changes in DNA methylation. It remains unclear whether these epigenetic …

Adequate maternal methyl-donor micronutrient (MET) intake is an important determinant of
the organ development and metabolic renovation of offspring. The mechanism involved in …

Aims/hypothesis Paternal high-fat diet prior to mating programmes impaired glucose
tolerance in female offspring. We examined whether the metabolic consequences in …

The pig is an excellent animal model for simulating human physiology and a major animal
for meat production and xenotransplantation. Therefore, researching porcine embryonic …

Gestational exposure to bisphenol A (BPA) can lead to offspring insulin resistance.
However, despite the role that the skeletal muscle plays in glucose homeostasis, it remains …

Folic acid (FA) plays multiple roles in many biological processes. Myoblast intakes FA
through endocytosis by folate receptor 1 (Folr1), which has vital role in regulating muscle …

猪的胚胎发育需要经历受精, 卵裂, 孵化, 形态转变, 附植, 器官分化等一系列重要的生理阶段.
虽然在胚胎发育过程中基因的严格表达与正确指导是胚胎能否正常发育的决定性条件 …

目的总结以双下肢乏力为主要表现的, 合并低叶酸血症的患者的临床特征. 方法选择自2017 年1
月—2020 年12 月在我院神经内科住院的患者, 分为3 组: 双下肢乏力伴叶酸缺乏组, 共23 例; …

Background Impaired skeletal muscle growth in utero can result in reduced birth weight and
pathogenesis of intrauterine growth restriction. Fetal and placental growth is influenced by …