Predictive biology is the next great chapter in synthetic and systems biology, particularly for
microorganisms. Tasks that once seemed infeasible are increasingly being realized such as …

The emergence and spread of antimicrobial resistance (AMR) among pathogenic bacteria
constitute an accelerating crisis for public health. The selective pressures caused by …

The emergence and rapid spread of antibiotic resistance seriously compromise the clinical
efficacy of current antibiotic therapies, representing a serious public health threat worldwide …

Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in
which a bacterial cell becomes insensitive to one (or even) more antibiotic (s). However, the …

Plasmid-mediated dissemination of antibiotic resistance among fecal Enterobacteriaceae in
natural ecosystems may contribute to the persistence of antibiotic resistance genes in …

Antibiotic resistance is a major challenge to public health, but human-caused environmental
changes have not been widely recognized as its drivers. Here, we provide a comprehensive …

The successful treatment of infectious diseases heavily relies on the therapeutic usage of
antibiotics. However, the high use of antibiotics in humans and animals leads to increasing …

Recently, extensive attention has been paid to antibiotic resistance genes (ARGs)
transmission. However, little available literature could be found about ARGs transmission in …

Highlights•Microbial HGT is a complex process influenced by a variety of modulating factors,
including cellular genetics and environmental conditions.•HGT dynamics are governed by …

The accelerated spread of antibiotic resistance genes (ARG) in the environment occurs
mainly through plasmid transfer facilitated via bacterial conjugation. To predict and efficiently …