Gentamicin (GNT) is an aminoglycoside antibiotic used for treatment of serious infections,
and the nephrotoxic adverse effect is one of the main therapeutic limitations. This study …

Background The cholestatic liver disease could develop in association with a wide range of
etiologies. The liver is the most affected organ by cholestasis. It has also been found that the …

Gentamicin-induced nephrotoxicity has been well documented, although the causing
mechanisms and preventative measures need further investigation. The current study aimed …

Acute kidney injury (AKI) is a serious disorder that accompanies rhabdomyolysis (RM). The
underlying mechanisms as well as protective approaches need to be investigated. This …

Background Gentamicin is widely used as an antibiotic for the treatment of gram negative
infections. Evidences indicates that oxidative stress is involved in gentamicin-induced …

Thymelaea microphylla Coss. et Dur (T. microphylla), a medicinal herb that grows in arid
and desert pastures, has been traditionally utilized by Moroccans to treat many diseases …

The gentamicin renal toxicity has been the focal point for much discussion. The objective of
this study was to investigate the impacts of Origanum vulgare L. extract and vitamin C on …

In Morocco, Raphanus sativus is a widespread traditional medicinal plant used to treat
various kidney diseases such as nephropathy. Objective: The present study aims to evaluate …

Background Aminoglycoside antibiotics, gentamicin (GM) owns the utmost nephrotoxic
potential than other antibiotics from the same category. To the other side, diosgenin (DG) …

Agmatine, a naturally occurring polyamine derived from arginine via arginine
decarboxylase, has been shown to play multifaceted roles in the mammalian body …