Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

W Jia, Y Li, KCP Cheung, X Zheng - Science China Life Sciences, 2024 - Springer
Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Gut microbiota bridges dietary nutrients and host immunity

L Fan, Y Xia, Y Wang, D Han, Y Liu, J Li, J Fu… - Science China Life …, 2023 - Springer
Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

Translocation of gut microbes to epididymal white adipose tissue drives lipid metabolism disorder under heat stress

ZC Deng, JC Yang, YX Huang, L Zhao, J Zheng… - Science China Life …, 2023 - Springer
Heat stress induces multi-organ damage and serious physiological dysfunction in mammals,
and gut bacteria may translocate to extra-intestinal tissues under heat stress pathology …

Exercise-induced microbial changes in preventing type 2 diabetes

T Yao, H Wang, K Lin, R Wang, S Guo, P Chen… - Science China Life …, 2024 - Springer
The metabolic benefits associated with long-term physical activity are well appreciated and
growing evidence suggests that it involves the gut microbiota. Here we re-evaluated the link …

Stachyose in combination with L. rhamnosus GG ameliorates acute hypobaric hypoxia-induced intestinal barrier dysfunction through alleviating inflammatory …

D Ren, M Ding, J Su, J Ye, X He, Y Zhang… - Free Radical Biology and …, 2024 - Elsevier
High altitude is closely related to intestinal mucosal damage and intestinal microbiota
imbalance, and there is currently no effective prevention and treatment measures. In this …

When smoke meets gut: deciphering the interactions between tobacco smoking and gut microbiota in disease development

B Chen, G Zeng, L Sun, C Jiang - Science China Life Sciences, 2024 - Springer
Tobacco smoking is a prevalent and detrimental habit practiced worldwide, increasing the
risk of various diseases, including chronic obstructive pulmonary disease (COPD) …

High-altitude and low-altitude adapted chicken gut-microbes have different functional diversity

NR Bhagat, P Chauhan, P Verma, A Mishra… - Scientific Reports, 2023 - nature.com
Recently, there has been considerable interest in the functions of gut microbiota in broiler
chickens in relation to their use as feed additives. However, the gut-microbiota of chickens …

Oxygen enrichment protects against intestinal damage and gut microbiota disturbance in rats exposed to acute high-altitude hypoxia

Q Ma, J Ma, J Cui, C Zhang, Y Li, J Liu, K Xie… - Frontiers in …, 2023 - frontiersin.org
Acute high-altitude hypoxia can lead to intestinal damage and changes in gut microbiota.
Sustained and reliable oxygen enrichment can resist hypoxic damage at high altitude to a …

Lactobacillus johnsonii YH1136 plays a protective role against endogenous pathogenic bacteria induced intestinal dysfunction by reconstructing gut microbiota in …

Z Wan, X Zhang, X Jia, Y Qin, N Sun, J Xin… - Frontiers in …, 2022 - frontiersin.org
Background Intestinal microbiota plays an important role in maintaining the microecological
balance of the gastrointestinal tract in various animals. Disturbances in the intestinal …

Review of the relationship and underlying mechanisms between the Qinghai–Tibet plateau and host intestinal flora

J Lv, P Qi, LH Bai, XD Yan, L Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
The intestinal microbial community is the largest ecosystem in the human body, in which the
intestinal flora plays a dominant role and has a wide range of biological functions. However …