Research progress on antidepressant effects and mechanisms of berberine

Y Gao, K Nie, H Wang, H Dong, Y Tang - Frontiers in Pharmacology, 2024 - frontiersin.org
Depression, a global health problem with growing prevalence, brings serious impacts on the
daily life of patients. However, the antidepressants currently used in clinical are not perfectly …

Therapeutic potential of Erxian decoction and its special chemical markers in depression: a review of clinical and preclinical studies

NX Zeng, H Li, MY Su, X Chen, XY Yang… - Frontiers in …, 2024 - frontiersin.org
The increasing prevalence of depression is a major societal burden. The etiology of
depression involves multiple mechanisms. Thus, the outcomes of the currently used …

Arctiin Mitigates Neuronal Injury by Modulating the P2X7R/NLPR3 Inflammasome Signaling Pathway

GN Jin, Y Wang, YM Liu, YN Lu, JM Lu, JH Wang… - Inflammation, 2024 - Springer
Depression, recognized globally as a primary cause of disability, has its pathogenesis
closely related to neuroinflammation and neuronal damage. Arctiin (ARC), the major …

The therapeutic potential of traditional Chinese medicine in depression: focused on the modulation of neuroplasticity

S Lv, N Yang, Y Lu, G Zhang, X Zhong, Y Cui… - Frontiers in …, 2024 - frontiersin.org
Depression, a mood disorder characterized by a persistent low mood and lack of enjoyment,
is considered the leading cause of non-fatal health losses worldwide. Neuroplasticity refers …

Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide‐Induced Sickness‐Like Behaviour in Mice

T Kodi, S Praveen, SK Paka, R Sankhe… - Advances in …, 2024 - Wiley Online Library
Sickness behaviour, a set of behavioural changes associated with neuroinflammation, is
expressed as decreased mobility and depressed behaviour. Activation of AMP‐activated …

The role and advance of ubiquitination and deubiquitination in depression pathogenesis and treatment

X Yan, Y Ma, J Yang, X Chang, S Shi… - Drug Development …, 2024 - Wiley Online Library
Depression is a common neuropsychiatric disease that is characterized by long‐term,
repeated low mood, pain and despair, pessimism, and even suicidal tendencies. Increasing …

Research progress on pharmacological effects and bioavailability of berberine

Y Cui, Q Zhou, M Jin, S Jiang, P Shang… - Naunyn-Schmiedeberg's …, 2024 - Springer
Berberine (BBR), a benzylisoquinoline alkaloid obtained from natural medicines such as
coptidis rhizoma, has a wide range of pharmacological activities such as protecting the …

Berberine Inhibits Hyperlipidemia-Associated Erectile Dysfunction Through the Mediation of miR-342-3p–Related Pathway

W Wu, J Li, Y Guo - Revista Brasileira de Farmacognosia, 2024 - Springer
Berberine has been found to improve diabetes-induced erectile dysfunction, but its role and
underlying molecular mechanism in hyperlipidemia-associated erectile dysfunction remain …

Effects of chronic unpredictable mild stress on gut sensation and function in male mice

F Liang, S Liu, H Zhang, R Xiang, M Xie, X He, S Wang… - Stress, 2024 - Taylor & Francis
Stress has been linked to the development of irritable bowel syndrome (IBS), and various
methods have been explored to model IBS in combination with other stimuli. However, it …