[HTML][HTML] Industry 4.0 for pharmaceutical manufacturing: Preparing for the smart factories of the future
NS Arden, AC Fisher, K Tyner, XY Lawrence… - International Journal of …, 2021 - Elsevier
Over the last two centuries, medicines have evolved from crude herbal and botanical
preparations into more complex manufacturing of sophisticated drug products and dosage …
preparations into more complex manufacturing of sophisticated drug products and dosage …
Role of biocatalysis in sustainable chemistry
RA Sheldon, JM Woodley - Chemical reviews, 2018 - ACS Publications
Based on the principles and metrics of green chemistry and sustainable development,
biocatalysis is both a green and sustainable technology. This is largely a result of the …
biocatalysis is both a green and sustainable technology. This is largely a result of the …
Pharma Industry 4.0: Literature review and research opportunities in sustainable pharmaceutical supply chains
B Ding - Process Safety and Environmental Protection, 2018 - Elsevier
The exploitation of the emerging technologies of Pharma Industry 4.0 facilitates sustainable
value creation, leads to more agile, smart and personalised pharma industry, and thereby, in …
value creation, leads to more agile, smart and personalised pharma industry, and thereby, in …
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
Pharmaceutical manufacturing typically uses batch processing at multiple locations.
Disadvantages of this approach include long production times and the potential for supply …
Disadvantages of this approach include long production times and the potential for supply …
[HTML][HTML] The rise of continuous flow biocatalysis–fundamentals, very recent developments and future perspectives
Biocatalysis community has witnessed a drastic increase in the number of studies for the use
of enzymes in continuously operated flow reactors. This significant interest arose from the …
of enzymes in continuously operated flow reactors. This significant interest arose from the …
Mechanochemistry can reduce life cycle environmental impacts of manufacturing active pharmaceutical ingredients
O Galant, G Cerfeda, AS McCalmont… - ACS Sustainable …, 2022 - ACS Publications
The scale-up of mechanochemical methods could play a transformative role in making
manufacturing processes in the pharmaceutical industry greener by eliminating solvent use …
manufacturing processes in the pharmaceutical industry greener by eliminating solvent use …
[HTML][HTML] Continuous manufacturing–the Green Chemistry promise?
Continuous manufacturing and Green Chemistry, are two promising approaches to
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …
Continuous crystallization processes in pharmaceutical manufacturing: A review
J Orehek, D Teslic, B Likozar - Organic Process Research & …, 2020 - ACS Publications
This scientific paper presents an overview of continuous solution crystallization in the
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …
pharmaceutical industry. Since the specific knowledge spectrum of precipitation is very …
Continuous flow biocatalysis
The continuous flow synthesis of active pharmaceutical ingredients, value-added chemicals,
and materials has grown tremendously over the past ten years. This revolution in chemical …
and materials has grown tremendously over the past ten years. This revolution in chemical …
Advanced real‐time process analytics for multistep synthesis in continuous flow
P Sagmeister, R Lebl, I Castillo, J Rehrl… - Angewandte Chemie …, 2021 - Wiley Online Library
In multistep continuous flow chemistry, studying complex reaction mixtures in real time is a
significant challenge, but provides an opportunity to enhance reaction understanding and …
significant challenge, but provides an opportunity to enhance reaction understanding and …