The role of autophagy in bone metabolism and clinical significance

J Wang, Y Zhang, J Cao, Y Wang, N Anwar, Z Zhang… - Autophagy, 2023 - Taylor & Francis
The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

[HTML][HTML] Cell death regulation: a new way for natural products to treat osteoporosis

Z Li, D Li, R Chen, S Gao, Z Xu, N Li - Pharmacological Research, 2023 - Elsevier
Osteoporosis is a common metabolic bone disease that results from the imbalance of
homeostasis within the bone. Intra-bone homeostasis is dependent on a precise dynamic …

Endoplasmic reticulum stress-mediated autophagy activation is involved in cadmium-induced ferroptosis of renal tubular epithelial cells

C Zhao, D Yu, Z He, L Bao, L Feng, L Chen… - Free Radical Biology …, 2021 - Elsevier
Acute cadmium (Cd) exposure is a significant risk factor for renal injury and lacks effective
treatment strategies. Ferroptosis is a recently identified iron-dependent form of nonapoptotic …

Autophagy and skin wound healing

H Ren, F Zhao, Q Zhang, X Huang, Z Wang - Burns & trauma, 2022 - academic.oup.com
Autophagy is a lysosome-dependent, self-renewal mechanism that can degrade and recycle
cellular components in eukaryotic cells to maintain the stability of the intracellular …

[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease

T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

[HTML][HTML] New insights into pathomechanisms and treatment possibilities for lung silicosis

J Adamcakova, D Mokra - International journal of molecular sciences, 2021 - mdpi.com
Inhalation of silica particles is an environmental and occupational cause of silicosis, a type
of pneumoconiosis. Development of the lung silicosis is a unique process in which the …

[HTML][HTML] The role of TNF-α in the fate regulation and functional reprogramming of mesenchymal stem cells in an inflammatory microenvironment

W Li, Q Liu, J Shi, X Xu, J Xu - Frontiers in Immunology, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) are pluripotent stem cells with multidirectional
differentiation potential and strong immunomodulatory capacity. MSCs have been widely …

Gold nanoparticles targeting the autophagy–lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: from …

Y Yin, BM Tian, X Li, YC Yu, DK Deng, LJ Sun, HL Qu… - Biomaterials, 2022 - Elsevier
Although substantial data indicate that the osteogenic potential of periodontal ligament stem
cells (PDLSCs) is compromised under inflammatory conditions, the underlying mechanism …

Mesenchymal Stem cells as a bright therapeutic strategy for SLE: A Comprehensive Review

HR Youshanlouei, H Valizadeh, A Tahavvori… - …, 2023 - search.proquest.com
Systemic lupus erythematosus (SLE) is a heterogeneous, chronic autoimmune disorder that
influences different systems. The pathogenesis of the SLE accompanies various T …

[HTML][HTML] Mesenchymal stem/stromal cells derived from human and animal perinatal tissues—origins, characteristics, signaling pathways, and clinical trials

M Kulus, R Sibiak, K Stefańska, M Zdun… - Cells, 2021 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are currently one of the most extensively
researched fields due to their promising opportunity for use in regenerative medicine. There …