[PDF][PDF] Hypothalamic survival circuits: blueprints for purposive behaviors

SM Sternson - Neuron, 2013 - cell.com
Neural processes that direct an animal's actions toward environmental goals are critical
elements for understanding behavior. The hypothalamus is closely associated with …

Neurohormonal functioning and sexual orientation: A theory of homosexuality–heterosexuality.

L Ellis, MA Ames - Psychological bulletin, 1987 - psycnet.apa.org
Following a historical sketch of attempts to explain homosexuality, we review evidence
indicating that the process of determining human sexual orientation is fundamentally the …

[HTML][HTML] Gene regulation by gonadal hormone receptors underlies brain sex differences

B Gegenhuber, MV Wu, R Bronstein, J Tollkuhn - Nature, 2022 - nature.com
Oestradiol establishes neural sex differences in many vertebrates 1, 2, 3 and modulates
mood, behaviour and energy balance in adulthood 4, 5, 6, 7, 8. In the canonical pathway …

Neural dynamics in the limbic system during male social behaviors

Z Guo, L Yin, V Diaz, B Dai, T Osakada, JE Lischinsky… - Neuron, 2023 - cell.com
Sexual and aggressive behaviors are vital for species survival and individual reproductive
success. Although many limbic regions have been found relevant to these behaviors, how …

[HTML][HTML] Estrogen masculinizes neural pathways and sex-specific behaviors

MV Wu, DS Manoli, EJ Fraser, JK Coats, J Tollkuhn… - Cell, 2009 - cell.com
Sex hormones are essential for neural circuit development and sex-specific behaviors. Male
behaviors require both testosterone and estrogen, but it is unclear how the two hormonal …

Androgens and the evolution of male-gender identity among male pseudohermaphrodites with 5α-reductase deficiency

J Imperato-McGinley, RE Peterson… - New England Journal …, 1979 - Mass Medical Soc
To determine the contribution of androgens to the formation of male-gender identity, we
studied male pseudohermaphrodites who had decreased dihydrotestosterone production …

A functional circuit underlying male sexual behaviour in the female mouse brain

T Kimchi, J Xu, C Dulac - Nature, 2007 - nature.com
In mice, pheromone detection is mediated by the vomeronasal organ and the main olfactory
epithelium. Male mice that are deficient for Trpc2, an ion channel specifically expressed in …

[PDF][PDF] Representing sex in the brain, one module at a time

CF Yang, NM Shah - Neuron, 2014 - cell.com
Sexually dimorphic behaviors, qualitative or quantitative differences in behaviors between
the sexes, result from the activity of a sexually differentiated nervous system. Sensory cues …

[PDF][PDF] The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors

SA Juntti, J Tollkuhn, MV Wu, EJ Fraser, T Soderborg… - Neuron, 2010 - cell.com
Testosterone and estrogen are essential for male behaviors in vertebrates. How these two
signaling pathways interact to control masculinization of the brain and behavior remains to …

Differentiation of coital behavior in mammals: a comparative analysis

MJ Baum - Neuroscience & Biobehavioral Reviews, 1979 - Elsevier
The evidence reviewed suggests that in all mammalian species the adult male's ability to
display masculine coital behavior depends in part on exposure of the developing brain to …