Distant metastasis is the main cause of death for cancer patients. Recently, the newly
discovered programmed cell death includes necroptosis, pyroptosis, and ferroptosis, which …

We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of
preclinical research in cancer biology. The initial aim of the project was to repeat 193 …

Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men
worldwide. Despite the presence of accumulated clinical strategies for PCa management …

Liver cancer is the second most frequent cause of cancer-related death globally. The main
histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes …

MicroRNAs (miRNAs) are endogenous and small non-coding RNAs that have been
identified as mediators of tumor suppression as well as stress responses mediated by p53 …

Globally, prostate cancer (PC) is leading cause of cancer-related mortality in men
worldwide. Despite significant advances in the treatment and management of this disease …

Genome-derived microRNAs (miRNAs or miRs) control post-transcriptional gene expression
critical for various cellular processes. Recently, we have invented a novel platform …

Uveal melanoma (UM) is the most common and aggressive primary intraocular tumor in
adults. UM is classified as a malignant tumor with a strong tendency of metastasis, which …

The present study aimed to investigate the effects of the long non‑coding RNA (lncRNA)
growth arrest‑specific transcript 5 (GAS5) on proliferation, apoptosis and the inflammatory …

The past two decades have seen extensive research done to pinpoint the role of microRNAs
(miRNAs) that have led to discovering thousands of miRNAs in humans. It is not, therefore …