Potential genetic and epigenetic mechanisms in insomnia: A systematic review

L Palagini, PA Geoffroy, PR Gehrman… - Journal of Sleep …, 2023 - Wiley Online Library
Insomnia is a stress‐related sleep disorder conceptualised within a diathesis‐stress
framework, which it is thought to result from predisposing factors interacting with …

Genetics and epigenetics of self‐injurious thoughts and behaviors: systematic review of the suicide literature and methodological considerations

S Mirza, AR Docherty, A Bakian, H Coon… - American Journal of …, 2022 - Wiley Online Library
Suicide is a multifaceted and poorly understood clinical outcome, and there is an urgent
need to advance research on its phenomenology and etiology. Epidemiological studies …

Selection of genetic instruments in Mendelian randomisation studies of sleep traits

V Paz, HS Dashti, S Burgess, V Garfield - Sleep medicine, 2023 - Elsevier
This review explores the criteria used for the selection of genetic instruments of sleep traits
in the context of Mendelian randomisation studies. This work was motivated by the fact that …

Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia

BJ Miller, WV McCall - Current opinion in psychiatry, 2023 - journals.lww.com
Meta-analysis of insomnia, suicide, and psychopathology in s... : Current Opinion in Psychiatry
Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia : Current Opinion …

Suicidal ideation and associated risk factors among COVID-19 patients who recovered from the first wave of the pandemic in Wuhan, China

X Chen, Z Dai, J Fu, M Si, S Jing, Y Wu… - … Journal of Medicine, 2023 - academic.oup.com
Background Symptoms of psychiatric, neurological, and physical illnesses with post-COVID
syndrome could increase suicidal ideation (SI) and behavior in Corona Virus Disease 2019 …

Leveraging genetic discoveries for sleep to determine causal relationships with common complex traits

S Sonti, SFA Grant - Sleep, 2022 - academic.oup.com
Sleep occurs universally and is a biological necessity for human functioning. The
consequences of diminished sleep quality impact physical and physiological systems such …

[HTML][HTML] Optimising the use of electronic medical records for large scale research in psychiatry

D Newby, N Taylor, DW Joyce… - Translational Psychiatry, 2024 - nature.com
The explosion and abundance of digital data could facilitate large-scale research for
psychiatry and mental health. Research using so-called “real world data”—such as …

Neuropsychiatric disorders, chronotype and sleep: A narrative review of GWAS findings and the application of Mendelian randomization to investigate causal …

S Crinion, DW Morris, LM Lopez - Genes, Brain and Behavior, 2024 - Wiley Online Library
Genome‐wide association studies (GWAS) have been important for characterizing the
genetic component and enhancing our understanding of the biological aetiology of both …

Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian …

B Cabrera-Mendoza, N Aydin, GR Fries… - …, 2024 - nature.com
Bipolar disorder (BD) and schizophrenia (SZ) are associated with higher odds of suicide
attempt (SA). In this study, we aimed to explore the effect of BD and SZ genetic liabilities on …

[HTML][HTML] Eyes wide open: sleep disturbance, not melatonin, is the real issue to address for suicide risk

S Diaz, M Grigg-Damberger - Journal of clinical sleep medicine, 2022 - jcsm.aasm.org
In this issue of the Journal of Clinical Sleep Medicine, Høier et al attempt to address
associations between melatonin use and suicidal behavior, based on data from a query of a …