Obstacles and opportunities in a forward vision for cancer nanomedicine
I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …
circulation to target tumours while sparing healthy tissues the toxicity of classic …
[HTML][HTML] Nanodelivery of nucleic acids
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
A global review on short peptides: Frontiers and perspectives
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …
entities via all domains of life and interfere with protein-protein interactions, which are …
Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency
Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
A forward vision for chemodynamic therapy: Issues and opportunities
P Zhao, H Li, W Bu - Angewandte Chemie International Edition, 2023 - Wiley Online Library
Since the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great
signs of progress have been made in the field of chemodynamic therapy (CDT). However …
signs of progress have been made in the field of chemodynamic therapy (CDT). However …
Nanoparticle toxicology
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
[HTML][HTML] Regulating trained immunity with nanomedicine
Trained immunity refers to a hyperresponsive functional state of the innate immune system,
which is induced by certain stimuli, such as infections or vaccination. Trained immunity plays …
which is induced by certain stimuli, such as infections or vaccination. Trained immunity plays …
[HTML][HTML] Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components
The utilization of nanomaterials in the biological and medical field is quickly progressing,
particularly in areas where traditional diagnostics and treatment approaches have limited …
particularly in areas where traditional diagnostics and treatment approaches have limited …