[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy

Q Xiao, X Li, Y Li, Z Wu, C Xu, Z Chen, W He - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

[HTML][HTML] The past, present, and future of breast cancer models for nanomedicine development

P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …

How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?

VT Cong, JL Houng, M Kavallaris, X Chen… - Chemical Society …, 2022 - pubs.rsc.org
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

[HTML][HTML] Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures

NH Khan, M Mir, L Qian, M Baloch, MFA Khan… - Journal of advanced …, 2022 - Elsevier
Background Skin cancer has been the leading type of cancer worldwide. Melanoma and
non-melanoma skin cancers are now the most common types of skin cancer that have been …

[HTML][HTML] Toxicity of manufactured nanomaterials

Y Liu, S Zhu, Z Gu, C Chen, Y Zhao - Particuology, 2022 - Elsevier
Manufactured nanomaterials with unique properties have been extensively applied in
various industrial, agricultural or medical fields. However, some of the properties have been …

[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

S Mazumdar, D Chitkara, A Mittal - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Transcytosis-enabled active extravasation of tumor nanomedicine

Q Zhou, J Li, J Xiang, S Shao, Z Zhou, J Tang… - Advanced Drug Delivery …, 2022 - Elsevier
Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

[HTML][HTML] Hyperthermia and smart drug delivery systems for solid tumor therapy

ALB Seynhaeve, M Amin, D Haemmerich… - Advanced Drug Delivery …, 2020 - Elsevier
Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …

Recent development of gold nanoparticles as contrast agents for cancer diagnosis

D Luo, X Wang, C Burda, JP Basilion - Cancers, 2021 - mdpi.com
Simple Summary The development of nanotechnology has brought revolution to the
diagnosis and therapy of diseases, with a high precision and efficacy. Because …

Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy

Q Zhou, C Dong, W Fan, H Jiang, J Xiang, N Qiu… - Biomaterials, 2020 - Elsevier
Nanotechnology-based drug delivery platforms have been explored for cancer treatments
and resulted in several nanomedicines in clinical uses and many in clinical trials. However …