Allergic diseases are significant diseases that affect many patients worldwide. In the past
few decades, the incidence of allergic diseases has increased significantly due to …

BACKGROUND: The goals of asthma treatment include preventing recurrent exacerbations.
Yet there is no consensus about the terminology for describing or defining “exacerbation” or …

Background: The fractional exhaled nitric oxide (FeNO) test is a point-of-care test that is
used in the assessment of asthma. Objective: To provide evidence-based clinical guidance …

Background Type 2 innate lymphoid cells (ILC2s) represent an important type 2 immune
cell. Glucocorticoid regulation of human ILC2s is largely unknown. Objective We sought to …

Rationale: The role of airway microbiome in corticosteroid response in asthma is unknown.
Objectives: To examine airway microbiome composition in patients with corticosteroid …

Rationale: Airway eosinophilia is typical of asthma, and many controller treatments target
eosinophilic disease. Asthma is clinically heterogeneous, however, and a subgroup of …

Importance In asthma and other diseases, vitamin D insufficiency is associated with adverse
outcomes. It is not known if supplementing inhaled corticosteroids with oral vitamin D 3 …

Asthma is a common heterogeneous disease with a complex pathophysiology that carries a
significant mortality rate and high morbidity. Current therapies based on inhaled …

Many patients with breathlessness and chronic obstructive lung disease are diagnosed with
either asthma, COPD, or—frequently—mixed disease. More commonly, patients with …

Objective To provide a clinical rationale for including impulse oscillometry (IOS) as a part of
standard office-based asthma assessment. Data Sources PubMed and Google search …