Regulatory effect of gut microbes on blood pressure

D Yan, Y Sun, X Zhou, W Si, J Liu… - Animal Models and …, 2022 - Wiley Online Library
Hypertension is an important global public health issue because of its high morbidity as well
as the increased risk of other diseases. Recent studies have indicated that the development …

Metabolites and hypertension: insights into hypertension as a metabolic disorder: 2019 Harriet Dustan Award

S Chakraborty, J Mandal, T Yang, X Cheng, JY Yeo… - …, 2020 - Am Heart Assoc
For over 100 years, essential hypertension has been researched from different perspectives
ranging from genetics, physiology, and immunology to more recent ones encompassing …

Does geographical variation confound the relationship between host factors and the human gut microbiota: a population-based study in China

S Sun, H Wang, MCB Tsilimigras, AG Howard, W Sha… - Bmj Open, 2020 - bmjopen.bmj.com
Objective The human gut microbiota plays important roles in human health but is also known
to be highly diverse between populations from different regions. Yet most studies …

The role of gut microbiota in hypertension pathogenesis and the efficacy of antihypertensive drugs

Y Xiong, Y Xiong, P Zhu, Y Wang, H Yang… - Current hypertension …, 2021 - Springer
Abstract Purpose of Heading To review the relationship between intestinal microbes and
hypertension and its impact on the efficacy of antihypertensive drugs, and help to address …

Exposure to amoxicillin in early life is associated with changes in gut microbiota and reduction in blood pressure: findings from a study on rat dams and offspring

S Galla, S Chakraborty, X Cheng, JY Yeo… - Journal of the …, 2020 - Am Heart Assoc
Background Pediatric hypertension is recognized as an emerging global health concern.
Although new guidelines are developed for facilitating clinical management, the reasons for …

Conjugated bile acids are nutritionally re-programmable antihypertensive metabolites

S Chakraborty, A Lulla, X Cheng, JY Yeo… - Journal of …, 2023 - journals.lww.com
Background: Hypertension is the largest risk factor affecting global mortality. Despite
available medications, uncontrolled hypertension is on the rise, whereby there is an urgent …

Comparative gut microbiome differences between high and low aortic arch calcification score in patients with chronic diseases

YH Liu, P Peng, WC Hung, PH Wu, CY Kao… - International Journal of …, 2023 - mdpi.com
Gut dysbiosis can induce chronic inflammation and contribute to atherosclerosis and
vascular calcification. The aortic arch calcification (AoAC) score is a simple, noninvasive …

Gut microbiota and host plasma metabolites in association with blood pressure in Chinese adults

Y Wang, H Wang, AG Howard, MCB Tsilimigras… - …, 2021 - Am Heart Assoc
Animal studies have revealed gut microbial and metabolic pathways of blood pressure (BP)
regulation, yet few epidemiological studies have collected microbiota and metabolomics …

Kidney microbiota dysbiosis contributes to the development of hypertension

XY Liu, J Li, Y Zhang, L Fan, Y Xia, Y Wu, J Chen… - Gut …, 2022 - Taylor & Francis
Gut microbiota dysbiosis promotes metabolic syndromes (eg, hypertension); however, the
patterns that drive hypertensive pathology and could be targeted for therapeutic intervention …

Maternal acetate supplementation reverses blood pressure increase in male offspring induced by exposure to minocycline during pregnancy and lactation

CN Hsu, HR Yu, JYH Chan, WC Lee, KLH Wu… - International Journal of …, 2022 - mdpi.com
Emerging evidence supports that hypertension can be programmed or reprogrammed by
maternal nutrition. Maternal exposures during pregnancy, such as maternal nutrition or …