Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …
Neurotoxicity of traffic-related air pollution
LG Costa, TB Cole, J Coburn, YC Chang, K Dao… - Neurotoxicology, 2017 - Elsevier
The central nervous system is emerging as an important target for adverse health effects of
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …
[HTML][HTML] Oxidative potential versus biological effects: a review on the relevance of cell-free/abiotic assays as predictors of toxicity from airborne particulate matter
J Øvrevik - International journal of molecular sciences, 2019 - mdpi.com
Background and Objectives: The oxidative potential (OP) of particulate matter (PM) in cell-
free/abiotic systems have been suggested as a possible measure of their biological …
free/abiotic systems have been suggested as a possible measure of their biological …
Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain
TB Cole, J Coburn, K Dao, P Roqué, YC Chang… - Toxicology, 2016 - Elsevier
In addition to increased morbidity and mortality caused by respiratory and cardiovascular
diseases, air pollution may also contribute to central nervous system (CNS) diseases. Traffic …
diseases, air pollution may also contribute to central nervous system (CNS) diseases. Traffic …
Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms
PJ Roqué, K Dao, LG Costa - Neurotoxicology, 2016 - Elsevier
In addition to the well-established effects of air pollution on the cardiovascular and
respiratory systems, emerging evidence has implicated it in inducing negative effects on the …
respiratory systems, emerging evidence has implicated it in inducing negative effects on the …
[HTML][HTML] Prenatal and early-life diesel exhaust exposure causes autism-like behavioral changes in mice
YC Chang, TB Cole, LG Costa - Particle and fibre toxicology, 2018 - Springer
Background Escalating prevalence of autism spectrum disorders (ASD) in recent decades
has triggered increasing efforts in understanding roles played by environmental risk factors …
has triggered increasing efforts in understanding roles played by environmental risk factors …
Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone
JL Coburn, TB Cole, KT Dao, LG Costa - Archives of toxicology, 2018 - Springer
Adult neurogenesis is the process by which neural stem cells give rise to new functional
neurons in specific regions of the adult brain, a process that occurs throughout life …
neurons in specific regions of the adult brain, a process that occurs throughout life …
Diesel exhaust induces mitochondrial dysfunction, hyperlipidemia, and liver steatosis
F Yin, R Gupta, L Vergnes, WS Driscoll… - … , and vascular biology, 2019 - Am Heart Assoc
Objective: Air pollution is associated with increased cardiovascular morbidity and mortality,
as well as dyslipidemia and metabolic syndrome. Our goal was to dissect the mechanisms …
as well as dyslipidemia and metabolic syndrome. Our goal was to dissect the mechanisms …
Prenatal and early life diesel exhaust exposure disrupts cortical lamina organization: Evidence for a reelin-related pathogenic pathway induced by interleukin-6
YC Chang, R Daza, R Hevner, LG Costa… - Brain, behavior, and …, 2019 - Elsevier
Several epidemiological studies have shown associations between developmental
exposure to traffic-related air pollution and increased risk for autism spectrum disorders …
exposure to traffic-related air pollution and increased risk for autism spectrum disorders …
Exposure to nanoparticles derived from diesel particulate filter equipped engine increases vulnerability to arrhythmia in rat hearts
S Rossi, A Buccarello, CC Malvezzi, S Pinelli… - Environmental …, 2021 - Elsevier
Air pollution is well recognized as a central player in cardiovascular disease. Exhaust
particulate from diesel engines (DEP) is rich in nanoparticles and may contribute to the …
particulate from diesel engines (DEP) is rich in nanoparticles and may contribute to the …