[HTML][HTML] Manipulating microbiota to treat atopic dermatitis: functions and therapies

MJ Alam, L Xie, YA Yap, FZ Marques, R Robert - Pathogens, 2022 - mdpi.com
Atopic dermatitis (AD) is a globally prevalent skin inflammation with a particular impact on
children. Current therapies for AD are challenged by the limited armamentarium and the …

Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE

L Bakaa, JM Pernica, RJ Couban, KJ Tackett… - Annals of Allergy …, 2022 - Elsevier
Background Bleach bathing is frequently recommended to treat atopic dermatitis (AD), but its
efficacy and safety are uncertain. Objective To systematically synthesize randomized …

[HTML][HTML] Anatomy promotes neutral coexistence of strains in the human skin microbiome

A Conwill, AC Kuan, R Damerla, AJ Poret, JS Baker… - Cell Host & Microbe, 2022 - cell.com
What enables strains of the same species to coexist in a microbiome? Here, we investigate
whether host anatomy can explain strain co-residence of Cutibacterium acnes, the most …

The skin microbiome in the first year of life and its association with atopic dermatitis

A Rapin, EM Rehbinder, M Macowan, C Pattaroni… - Allergy, 2023 - Wiley Online Library
Background Early‐life microbial colonization of the skin may modulate the immune system
and impact the development of atopic dermatitis (AD) and allergic diseases later in life. To …

[HTML][HTML] The Disease with a Thousand Faces and the Human Microbiome—A Physiopathogenic Intercorrelation in Pediatric Practice

VV Lupu, LI Butnariu, S Fotea, ID Morariu, MC Badescu… - Nutrients, 2023 - mdpi.com
Numerous interrelationships are known in the literature that have the final effect of
unmasking or influencing various pathologies. Among these, the present article aims to …

[HTML][HTML] Unlocking the potential of the human microbiome for identifying disease diagnostic biomarkers

R Hajjo, DA Sabbah, AQ Al Bawab - Diagnostics, 2022 - mdpi.com
The human microbiome encodes more than three million genes, outnumbering human
genes by more than 100 times, while microbial cells in the human microbiota outnumber …

[HTML][HTML] Bleach baths enhance skin barrier, reduce itch but do not normalize skin dysbiosis in atopic dermatitis

A Stolarczyk, N Perez-Nazario, SA Knowlden… - Archives of …, 2023 - Springer
Studies have demonstrated that bleach baths improve atopic dermatitis (AD) severity;
however, the effects on itch, skin barrier, and cutaneous microbial composition are less …

The dynamic balance of the skin microbiome across the lifespan

EC Townsend, LR Kalan - Biochemical Society Transactions, 2023 - portlandpress.com
For decades research has centered on identifying the ideal balanced skin microbiome that
prevents disease and on developing therapeutics to foster this balance. However, this single …

[HTML][HTML] The skin microbiome: current techniques, challenges, and future directions

TM Santiago-Rodriguez, B Le François, JM Macklaim… - Microorganisms, 2023 - mdpi.com
Skin acts as a barrier that promotes the colonization of bacteria, fungi, archaea, and viruses
whose membership and function may differ depending on the various specialized niches or …

Co-occurrence network analysis reveals the alterations of the skin microbiome and metabolome in adults with mild to moderate atopic dermatitis

PW P. Gomes, H Mannochio-Russo, J Mao, HN Zhao… - Msystems, 2024 - Am Soc Microbiol
Skin microbiome can be altered in patients with atopic dermatitis (AD). An understanding of
the changes from healthy to atopic skin can help develop new targets for treatment by …