Research into the molecular genetics of osteoarthritis (OA) has been substantially bolstered
in the past few years by the implementation of powerful genome-wide scans that have …

Osteoarthritis (OA), the most ubiquitous degenerative disease affecting the entire joint, is
characterized by cartilage degradation and synovial inflammation. Although the …

Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …

Objective In this review, we have highlighted advances in genetics, genomics and
epigenetics in the field of osteoarthritis (OA) over the past year. Methods A literature search …

Chronic inflammation is deeply involved in various human disorders, such as cancer,
neurodegenerative disorders, and metabolic disorders. Induction of epigenetic alterations …

Osteoarthritis (OA) is the most common type of arthritis and no longer is considered as an
absolute consequence of joint mechanical use (wear and tear); rather recent data …

This “year in review” provides a summary of the research findings on the topic of genetics,
genomics and epigenetics for osteoarthritis (OA) between Mar 2021–Apr 2022. A search …

Osteoarthritis (OA) is a bone and joint disease with pathological characteristics such as
articular cartilage degeneration injury and synovial and subchondral bone reactive …

Our study aimed to identify differentially methylated regions (ie, genomic region where
multiple adjacent CpG sites show differential methylation) and their enriched genomic …

Osteoarthritis (OA) is a common type of arthritis. Chronic inflammation is an important
contributor to the pathogenesis of OA. The maturation and secretion of proinflammatory …