When caloric intake exceeds caloric expenditure, the positive caloric balance and storage of
energy in adipose tissue often causes adipocyte hypertrophy and visceral adipose tissue …

The importance of β-adrenergic signaling in the heart has been well documented, but it is
only more recently that we have begun to understand the importance of this signaling …

Obesity is associated with low-grade inflammation, insulin resistance, type 2 diabetes, and
cardiovascular disease. This study investigated the effect of a 15-wk lifestyle intervention …

This study was conducted to test the hypothesis that dietary supplementation of arginine, the
physiologic precursor of nitric oxide (NO), reduces fat mass in the Zucker diabetic fatty (ZDF) …

The evidence about the health benefits of regular physical activity is well established.
Exercise intensity is a significant variable and structured high-intensity interval training (HIIT) …

Background Muscle strength and body size may be associated with coronary heart disease
(CHD) and stroke risk. However, perhaps because of a low number of cases, existing …

Fatty acids can activate proinflammatory pathways leading to the development of insulin
resistance, but the mechanism is undiscovered. Toll like receptor 2 (TLR2) recognizes lipids …

Interleukin (IL)-6 is a proinflammatory cytokine shown to modify insulin sensitivity. Elevated
plasma levels of IL-6 are observed in insulin-resistant states. Interestingly, plasma IL-6 …

Obesity and insulin resistance cause serious consequences to human health. To study
effects of skeletal muscle growth on obesity prevention, we focused on a key gene of …

Fatty acids are the major source of energy for most tissues during periods of negative energy
balance; however, fatty acids can, in some circumstances, have pathological effects. Fatty …