[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

[HTML][HTML] Corneal endothelial dysfunction: Evolving understanding and treatment options

MO Price, JS Mehta, UV Jurkunas… - Progress in retinal and eye …, 2021 - Elsevier
The cornea is exquisitely designed to protect the eye while transmitting and focusing
incoming light. Precise control of corneal hydration by the endothelial cell layer that lines the …

Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications

M Rizwan, GSL Peh, HP Ang, NC Lwin, K Adnan… - Biomaterials, 2017 - Elsevier
Naturally-bioactive hydrogels like gelatin provide favorable properties for tissue-engineering
but lack sufficient mechanical strength for use as implantable tissue engineering substrates …

[HTML][HTML] Regulatory compliant tissue-engineered human corneal endothelial grafts restore corneal function of rabbits with bullous keratopathy

GSL Peh, HP Ang, CN Lwin, K Adnan, BL George… - Scientific reports, 2017 - nature.com
Corneal transplantation is the only treatment available to restore vision for individuals with
blindness due to corneal endothelial dysfunction. However, severe shortage of available …

[HTML][HTML] Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion

RF Frausto, VS Swamy, GSL Peh, PM Boere… - Scientific reports, 2020 - nature.com
The advent of cell culture-based methods for the establishment and expansion of human
corneal endothelial cells (CEnC) has provided a source of transplantable corneal …

Decellularization and recellularization of cornea: Progress towards a donor alternative

J Fernández-Pérez, M Ahearne - Methods, 2020 - Elsevier
The global shortage of donor corneas for transplantation has led to corneal bioengineering
being investigated as a method to generate transplantable tissues. Decellularized corneas …

Corneal endothelium tissue engineering: An evolution of signaling molecules, cells, and scaffolds toward 3D bioprinting and cell sheets

M Khalili, M Asadi, H Kahroba… - Journal of Cellular …, 2021 - Wiley Online Library
Cornea is an avascular and transparent tissue that focuses light on retina. Cornea is
supported by the corneal‐endothelial layer through regulation of hydration homeostasis …

[HTML][HTML] Comprehensive review of the state-of-the-art in corneal 3D bioprinting, including regulatory aspects

H Gómez-Fernández, F Alhakim-Khalak… - International Journal of …, 2024 - Elsevier
The global shortage of corneal transplants has spurred an urgency in the quest for efficient
treatments. This systematic review not only provides a concise overview of the current …

Electro-spun membranes as scaffolds for human corneal endothelial cells

M Kruse, P Walter, B Bauer, S Rütten… - Current eye …, 2018 - Taylor & Francis
Background: Corneal endothelial dysfunction remains the most frequent indication for
corneal transplantation, limited by donor material shortage, poor long-term graft survival, or …

[HTML][HTML] Fuchs dystrophy and cataract: diagnosis, evaluation and treatment

M Ali, K Cho, D Srikumaran - Ophthalmology and Therapy, 2023 - Springer
Corneal endothelium plays an important role in maintaining hydration homeostasis and
clarity of the cornea. Fuchs endothelial corneal dystrophy (FECD) affects the corneal …