Objectives Prevention of obesity should start as early as possible after birth. We aimed to
build clinically useful equations estimating the risk of later obesity in newborns, as a first step …

Background: Several studies have investigated the effect of known adult body mass index
(BMI) associated single nucleotide polymorphisms (SNPs) on BMI in childhood. There has …

To map the genetics of gene expression in metabolically relevant tissues and investigate the
diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we …

The genetic contribution to interindividual variation in common obesity has been estimated
at 40–70%. Yet, despite a relatively high heritability, the search for obesity susceptibility …

Aging leads to the disruption of the homeostatic balance of multiple biological systems. In
bone marrow multipotent mesenchymal cells undergo differentiation into various anchorage …

Vitamin E (VE) has a recognized leading role as a contributor to the protection of cell
constituents from oxidative damage. However, evidence suggests that the health benefits of …

Background Genome-wide studies have identified several common genetic variants that are
robustly associated with adult obesity risk. Exploration of these genotype associations in …

The G-protein-coupled receptor accessory protein MRAP2 is implicated in energy control in
rodents, notably via the melanocortin-4 receptor. Although some MRAP2 mutations have …

Context: Obesity in adults is associated with shorter mean leukocyte telomere length (LTL), a
marker of biological age that is also associated with age-related conditions including …

The first intron of FTO contains common single nucleotide polymorphisms associated with
body weight and adiposity in humans. In an effort to identify the molecular basis for this …