Current state of Alzheimer's fluid biomarkers

JL Molinuevo, S Ayton, R Batrla, MM Bednar… - Acta …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Amsterdam dementia cohort: performing research to optimize care

WM Van Der Flier, P Scheltens - Journal of Alzheimer's …, 2018 - content.iospress.com
The Alzheimer center of the VU University Medical Center opened in 2000 and was initiated
to combine both patient care and research. Together, to date, all patients forming the …

Are dementia with Lewy bodies and Parkinson's disease dementia the same disease?

KA Jellinger, AD Korczyn - BMC medicine, 2018 - Springer
Abstract Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD), which share many clinical, neurochemical, and morphological features, have been …

Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies

KA Jellinger - Journal of neural transmission, 2018 - Springer
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

Psychosis in neurodegenerative disease: differential patterns of hallucination and delusion symptoms

G Naasan, SM Shdo, EM Rodriguez, S Spina… - Brain, 2021 - academic.oup.com
Although psychosis is a defining feature of Lewy body disease, psychotic symptoms occur in
a subset of patients with every major neurodegenerative disease. Few studies, however …

[HTML][HTML] The contribution of tau, amyloid-beta and alpha-synuclein pathology to dementia in Lewy body disorders

DJ Irwin, HI Hurtig - Journal of Alzheimer's disease & Parkinsonism, 2018 - ncbi.nlm.nih.gov
Parkinson's Disease (PD) and the closely related Dementia with Lewy Bodies (DLB) are due
to the accumulation of pathogenic alpha-synuclein protein in brain cells manifest by …

Association of plasma p-tau181 and p-tau231 concentrations with cognitive decline in patients with probable dementia with Lewy bodies

MC Gonzalez, NJ Ashton, BF Gomes… - JAMA …, 2022 - jamanetwork.com
Importance Plasma phosphorylated tau (p-tau) has proven to be an accurate biomarker for
Alzheimer disease (AD) pathologic characteristics, offering a less expensive and less …

[HTML][HTML] Alzheimer disease overview

TD Bird - GeneReviews®[Internet], 2018 - ncbi.nlm.nih.gov
Alzheimer Disease Overview - GeneReviews® - NCBI Bookshelf US flag An official website of
the United States government Here's how you know NIH NLM Logo Access keys NCBI …

β-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies

D Ferreira, SA Przybelski, TG Lesnick, AW Lemstra… - Neurology, 2020 - AAN Enterprises
Objective In a multicenter cohort of probable dementia with Lewy bodies (DLB), we tested
the hypothesis that β-amyloid and tau biomarker positivity increases with age, which is …

Pathological influences on clinical heterogeneity in Lewy body diseases

DG Coughlin, HI Hurtig, DJ Irwin - Movement Disorders, 2020 - Wiley Online Library
ABSTRACT PD, PD with dementia, and dementia with Lewy bodies are clinical syndromes
characterized by the neuropathological accumulation of alpha‐synuclein in the CNS that …