Although infectiological stimuli, environmental factors and genotypic features are known to
contribute to the initiation and perpetuation of systemic sclerosis (SSc), its etiology still …

Chronic inflammation can lead to altered extracellular matrix deposition and ultimately
fibrosis. Interleukin‐13 (IL‐13) is a cytokine that was found to promote IgE class switching …

Systemic sclerosis (SSc) is an autoimmune, multi-organ, connective tissue disease
associated with significant morbidity and mortality. Conventional immunosuppressive …

We aimed to investigate the possible association of the inactive, dephosphorylated,
uncarboxylated matrix Gla protein (dp-ucMGP) with oxidized low-density lipoprotein (ox …

Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterised by
biochemical evidence of cholestasis, elevated alkaline phosphatase levels and the …

Although immunosuppressive strategies to treat patients with systemic sclerosis and allied
conditions are largely disappointing, thus indicating a permissive rather than causative role …

Systemic sclerosis (SSc) is a severe autoimmune disorder characterized by vasculopathy
and multi-organ fibrosis; its etiology and pathogenesis are still largely unknown. Herpesvirus …

Objective The role of tumor necrosis factor (TNF) in systemic sclerosis (SSc) remains
controversial. The present study was undertaken to investigate the influence of TNF receptor …

Objective To characterise global chemokine expression in systemic sclerosis (SSc) skin in
order to better understand the relationship between chemokine expression and vascular …

The etiology and pathogenesis of human autoimmune diseases remain unknown despite
intensive investigations. Although remarkable progress has been accomplished through …