Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside
Y Xiong, Q Feng, L Lu, X Qiu, S Knoedler… - Advanced …, 2024 - Wiley Online Library
Chronic wounds are characterized by delayed and dysregulated healing processes. As
such, they have emerged as an increasingly significant threat. The associated morbidity and …
such, they have emerged as an increasingly significant threat. The associated morbidity and …
Atomic-level design of metalloenzyme-like active pockets in metal–organic frameworks for bioinspired catalysis
Natural metalloenzymes with astonishing reaction activity and specificity underpin essential
life transformations. Nevertheless, enzymes only operate under mild conditions to keep …
life transformations. Nevertheless, enzymes only operate under mild conditions to keep …
An immunomodulatory hydrogel by hyperthermia‐assisted self‐cascade glucose depletion and ROS scavenging for diabetic foot ulcer wound therapeutics
X Qi, E Cai, Y Xiang, C Zhang, XX Ge… - Advanced …, 2023 - Wiley Online Library
Current therapeutic protocols for diabetic foot ulcers (DFUs), a severe and rapidly growing
chronic complication in diabetic patients, remain nonspecific. Hyperglycemia‐caused …
chronic complication in diabetic patients, remain nonspecific. Hyperglycemia‐caused …
A whole‐course‐repair system based on neurogenesis‐angiogenesis crosstalk and macrophage reprogramming promotes diabetic wound healing
Diabetic wound (DW) therapy is currently a big challenge in medicine and strategies to
enhance neurogenesis and angiogenesis have appeared to be a promising direction …
enhance neurogenesis and angiogenesis have appeared to be a promising direction …
Ultrasound-augmented multienzyme-like nanozyme hydrogel spray for promoting diabetic wound healing
L Shang, Y Yu, Y Jiang, X Liu, N Sui, D Yang, Z Zhu - ACS nano, 2023 - ACS Publications
Treatment of diabetic foot ulcers (DFU) needs to reduce inflammation, relieve hypoxia, lower
blood glucose, promote angiogenesis, and eliminate pathogenic bacteria, but the …
blood glucose, promote angiogenesis, and eliminate pathogenic bacteria, but the …
Engineered multifunctional zinc–organic framework-based aggregation-induced emission nanozyme for accelerating spinal cord injury recovery
Functional recovery following a spinal cord injury (SCI) is challenging. Traditional drug
therapies focus on the suppression of immune responses; however, strategies for alleviating …
therapies focus on the suppression of immune responses; however, strategies for alleviating …
Cu-GA-coordination polymer nanozymes with triple enzymatic activity for wound disinfection and accelerated wound healing
H Tian, J Yan, W Zhang, H Li, S Jiang, H Qian, X Chen… - Acta Biomaterialia, 2023 - Elsevier
During the past few years, bacterial infection and oxidative stress have become important
issues for wound healing. However, the emergence of numerous drug-resistant superbugs …
issues for wound healing. However, the emergence of numerous drug-resistant superbugs …
An All‐in‐One “4A Hydrogel”: through First‐Aid Hemostatic, Antibacterial, Antioxidant, and Angiogenic to Promoting Infected Wound Healing
S Hu, Z Yang, Q Zhai, D Li, X Zhu, Q He, L Li… - Small, 2023 - Wiley Online Library
Currently used wound dressings are ineffective. Hence, there is a need to develop introduce
a high‐performance medicament with multiple functions including rapid hemostasis and …
a high‐performance medicament with multiple functions including rapid hemostasis and …
[HTML][HTML] MOF-derived bimetallic nanozyme to catalyze ROS scavenging for protection of myocardial injury
K Xiang, H Wu, Y Liu, S Wang, X Li, B Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Myocardial injury triggers intense oxidative stress, inflammatory response, and
cytokine release, which are essential for myocardial repair and remodeling. Excess reactive …
cytokine release, which are essential for myocardial repair and remodeling. Excess reactive …
Nanozyme‐Cosmetic Contact Lenses for Ocular Surface Disease Prevention
Q Liu, S Zhao, Y Zhang, Q Fang, W Liu… - Advanced …, 2023 - Wiley Online Library
Efficiently balancing excess reactive oxygen species (ROS) caused by various factors on the
ocular surface is a promising strategy for preventing the development of ocular surface …
ocular surface is a promising strategy for preventing the development of ocular surface …