Peptide-drug conjugates: a new hope for cancer management

VP Chavda, HK Solanki, M Davidson… - Molecules, 2022 - mdpi.com
Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Challenges in delivering therapeutic peptides and proteins: A silk-based solution

J Wu, JK Sahoo, Y Li, Q Xu, DL Kaplan - Journal of Controlled Release, 2022 - Elsevier
Peptide-and protein-based therapeutics have drawn significant attention over the past few
decades for the treatment of infectious diseases, genetic disorders, oncology, and many …

[HTML][HTML] Immunomodulatory peptides—A promising source for novel functional food production and drug discovery

M Pavlicevic, N Marmiroli, E Maestri - Peptides, 2022 - Elsevier
Immunomodulatory peptides are a complex class of bioactive peptides that encompasses
substances with different mechanisms of action. Immunomodulatory peptides could also be …

[HTML][HTML] Peptide-based targeting of immunosuppressive cells in cancer

NT Trac, EJ Chung - Bioactive materials, 2020 - Elsevier
Cancer progression is marked by the infiltration of immunosuppressive cells, such as tumor-
associated macrophages (TAMs), regulatory T lymphocytes (Tregs), and myeloid-derived …

Immunotherapies inducing immunogenic cell death in cancer: insight of the innate immune system

KM Calvillo-Rodríguez, HY Lorenzo-Anota… - Frontiers in …, 2023 - frontiersin.org
Cancer immunotherapies include monoclonal antibodies, cytokines, oncolytic viruses,
cellular therapies, and other biological and synthetic immunomodulators. These are …

Peptides and peptidomimetics as potential antiobesity agents: overview of current status

MS Kumar - Frontiers in nutrition, 2019 - frontiersin.org
There is a high occurrence of obesity worldwide without many new medications being
approved for its treatment. Therefore, there is an urgent need to introduce new approaches …

Bioactive peptides in fermented foods and their application: A critical review

R Chourasia, L Chiring Phukon, MM Abedin… - Systems Microbiology …, 2023 - Springer
Bioactive peptides are released during the production of fermented dairy, vegetables, fruits,
legumes, fish, and meat products. The proteolytic specificity of lactic acid bacteria, Bacillus …

Artificial intelligence and machine learning for protein toxicity prediction using proteomics data

S Vishnoi, H Matre, P Garg… - Chemical Biology & Drug …, 2020 - Wiley Online Library
Instead of only focusing on the targeted drug delivery system, researchers have a great
interest in developing peptide‐based therapies for the procurement of numerous class of …

Bioactive peptides: Synthesis, applications, and associated challenges

A Alzaydi, RI Barbhuiya, W Routray… - Food …, 2023 - Wiley Online Library
Bioactive peptides (BPs) are chains of amino acids linked together by peptide bonds and
arranged in a specific way. These peptides are important to human health and can be used …

How times have changed! A cornucopia of antigens for membranous nephropathy

TN Caza, LF Al-Rabadi, LH Beck Jr - Frontiers in Immunology, 2021 - frontiersin.org
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the
majority of primary (idiopathic) cases of membranous nephropathy (MN) has been followed …