Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Mesenchymal stem cell (MSC) therapies have been used as cell-based treatments for
decades, owing to their anti-inflammatory, immunomodulatory, and regenerative properties …

The role of the 6 ″-OH (ω-OH) group in the antioxidant activity of flavonoid glycosides has
been largely overlooked. Herein, we selected quercitrin (quercetin-3-O-rhamnoside) and …

Abstract Chitosan/Gelatin (CS: Gel) scaffolds were fabricated by chemical crosslinking with
glutaraldehyde or genipin by freeze drying. Both crosslinked CS: Gel scaffold types with a …

Osteogenesis imperfecta (OI) is a disease caused by mutations in different genes resulting
in mild, severe, or lethal forms. With no cure, researchers have investigated the use of cell …

The transplantation of tissue-engineered scaffolds with stem cells is a promising therapeutic
approach for bone defect repair. To improve the therapeutic efficacy of this approach, in this …

Background Given the limitations of current therapies for the reconstruction of bone defects,
regenerative medicine has arisen as a new therapeutic strategy along with mesenchymal …

Mesenchymal stem cells (MSCs), well-studied adult stem cells in various tissues, possess
multi-lineage differentiation potential and anti-inflammatory properties. MSCs have been …

Vascular endothelial cell growth factor C (VEGF-C) is a member of the VEGF family and
plays a role in a variety of biological activities including lymphangiogenesis, angiogenesis …

Abstract Bone morphogenetic protein-7 (BMP-7) plays a pivotal role in the transformation of
mesenchymal stem cells (MSCs) into bone. However, its impact is hampered due to its short …