Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …

Alcoholic liver disease (ALD) is a multifaceted process that involves excessive lipid, reactive
oxygen species (ROS) production, unbalanced mitochondrial homeostasis, and ultimate cell …

Nonalcoholic fatty liver disease (NAFLD) includes a broad spectrum of liver dysfunctions
and it is predicted to become the primary cause of liver failure and hepatocellular carcinoma …

Recent reports indicated that mitophagy protects against alcohol-induced liver injury, which
helps remove damaged mitochondria to reduce the accumulation of reactive oxygen species …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …

Damage-associated molecular patterns are signalling molecules involved in inflammatory
responses and restoration of homeostasis. Chronic release of these molecules can also …