[HTML][HTML] The cardiovascular system in space: focus on in vivo and in vitro studies

R Baran, S Marchal, S Garcia Campos, E Rehnberg… - Biomedicines, 2021 - mdpi.com
On Earth, humans are subjected to a gravitational force that has been an important
determinant in human evolution and function. During spaceflight, astronauts are subjected to …

[HTML][HTML] Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro

B Prasad, D Grimm, SM Strauch, GS Erzinger… - International journal of …, 2020 - mdpi.com
All life forms have evolved under the constant force of gravity on Earth and developed ways
to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …

[HTML][HTML] Wide range applications of spirulina: from earth to space missions

G Fais, A Manca, F Bolognesi, M Borselli, A Concas… - Marine Drugs, 2022 - mdpi.com
Spirulina is the most studied cyanobacterium species for both pharmacological applications
and the food industry. The aim of the present review is to summarize the potential benefits of …

Leveraging spaceflight to advance cardiovascular research on earth

JM Scott, J Stoudemire, L Dolan, M Downs - Circulation research, 2022 - Am Heart Assoc
The direct (eg, radiation, microgravity) and indirect (eg, lifestyle perturbations) effects of
spaceflight extend across multiple systems resulting in whole-organism cardiovascular …

Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin …

J Hirayama, A Hattori, A Takahashi… - Journal of pineal …, 2023 - Wiley Online Library
Exposure to the space environment induces a number of pathophysiological outcomes in
astronauts, including bone demineralization, sleep disorders, circadian clock dysregulation …

[HTML][HTML] What can biofabrication do for space and what can space do for biofabrication?

L Moroni, K Tabury, H Stenuit, D Grimm, S Baatout… - Trends in …, 2022 - cell.com
Biofabrication in space is one of the novel promising and prospective research directions in
the rapidly emerging field of space STEM. There are several advantages of biofabrication in …

[HTML][HTML] Small tissue chips with big opportunities for space medicine

X Mu, W He, VAM Rivera, RAD De Alba… - Life sciences in space …, 2022 - Elsevier
The spaceflight environment, including microgravity and radiation, may have considerable
effects on the health and performance of astronauts, especially for long-duration and Martian …

[HTML][HTML] Microgravity-related changes in bone density and treatment options: A systematic review

R Baran, M Wehland, H Schulz, M Heer… - International Journal of …, 2022 - mdpi.com
Space travelers are exposed to microgravity (µ g), which induces enhanced bone loss
compared to the age-related bone loss on Earth. Microgravity promotes an increased bone …

[HTML][HTML] A new era for space life science: international standards for space omics processing

L Rutter, R Barker, D Bezdan, H Cope, SV Costes… - Patterns, 2020 - cell.com
Space agencies have announced plans for human missions to the Moon to prepare for
Mars. However, the space environment presents stressors that include radiation …

[HTML][HTML] Physiological alterations in relation to space flight: the role of nutrition

S Chaloulakou, KA Poulia, D Karayiannis - Nutrients, 2022 - mdpi.com
Astronauts exhibit several pathophysiological changes due to a variety of stressors related
to the space environment, including microgravity, space radiation, isolation, and …