During development, functional structures must form with the correct three-dimensional
geometry composed of the correct cell types. In many cases cell types are specified at …

Ocular lens development represents an advantageous system in which to study regulatory
mechanisms governing cell fate decisions, extracellular signaling, cell and tissue …

Normal tables of development are essential for studies of embryogenesis, serving as an
important resource for model organisms, including the frog Xenopus laevis. Xenopus has …

Considerable progress has been made in identifying signaling pathways that direct the
differentiation of human pluripotent stem cells (hPSCs) into specialized cell types, including …

The inner ear contains sensory epithelia that detect head movements, gravity and sound. It
is unclear how to develop these sensory epithelia from pluripotent stem cells, a process that …

The vertebrate 'neural plate border'is a transient territory located at the edge of the neural
plate containing precursors for all ectodermal derivatives: the neural plate, neural crest …

The UV-and sensor-induced interferences to living systems pose a barrier for in vivo Zn2+
imaging. In this work, an intramolecular charge transfer (ICT) fluorophore of smaller aromatic …

Pain perception has evolved as a warning mechanism to alert organisms to tissue damage
and dangerous environments,. In humans, however, undesirable, excessive or chronic pain …

The lateral-line system is a simple sensory system comprising a number of discrete sense
organs, the neuromasts, distributed over the body of fish and amphibians in species-specific …

The inner ear is one of the most morphologically elaborate tissues in vertebrates, containing
a group of mechanosensitive sensory organs that mediate hearing and balance. These …