Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

Neurobiology of loneliness, isolation, and loss: integrating human and animal perspectives

EM Vitale, AS Smith - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
In social species such as humans, non-human primates, and even many rodent species,
social interaction and the maintenance of social bonds are necessary for mental and …

Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial

H Yamasue, M Kojima, H Kuwabara, M Kuroda… - Brain, 2022 - academic.oup.com
Although intranasal oxytocin is expected to be a novel therapy for the core symptoms of
autism spectrum disorder, which has currently no approved medication, the efficacy of …

Kinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men

J Lieberz, D Scheele, FB Spengler… - …, 2020 - nature.com
Accumulating evidence suggests that intranasal oxytocin (OXT; 24 IU) reduces amygdala
responses to fear-related stimuli in men, while exerting inverse effects in women. However …

Social approach and social vigilance are differentially regulated by oxytocin receptors in the nucleus accumbens

AV Williams, N Duque-Wilckens… - …, 2020 - nature.com
Oxytocin is currently being considered as a novel therapeutic for anxiety disorders due to its
ability to promote affiliative behaviors. In the nucleus accumbens (NAc) activation of oxytocin …

Pandemic leadership: sex differences and their evolutionary–developmental origins

S Luoto, MAC Varella - Frontiers in psychology, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global societal, economic, and social upheaval
unseen in living memory. There have been substantial cross-national differences in the …

Social cognitive neuroscience in the digital age

MM Doheny, NR Lighthall - Frontiers in Human Neuroscience, 2023 - frontiersin.org
Human interactions are increasingly taking place from a distance through methods of remote
interpersonal communication like video chatting and social media. While remote …

Social selectivity and social motivation in voles

AK Beery, SA Lopez, KL Blandino, NS Lee… - Elife, 2021 - elifesciences.org
Selective relationships are fundamental to humans and many other animals, but
relationships between mates, family members, or peers may be mediated differently. We …

Sex-dependent effects of social status on the regulation of arginine-vasopressin (AVP) V1a, oxytocin (OT), and serotonin (5-HT) 1A receptor binding and aggression in …

ZA Grieb, AP Ross, KE McCann, S Lee, M Welch… - Hormones and …, 2021 - Elsevier
Dominance status in hamsters is driven by interactions between arginine-vasopressin V1a,
oxytocin (OT), and serotonin 1A (5-HT1A) receptors. Activation of V1a and OT receptors in …

Molecular and neurocircuitry mechanisms of social avoidance

AK Gellner, J Voelter, U Schmidt, EC Beins… - Cellular and Molecular …, 2021 - Springer
Humans and animals live in social relationships shaped by actions of approach and
avoidance. Both are crucial for normal physical and mental development, survival, and well …