Anabolic–androgenic steroids: How do they work and what are the risks?

P Bond, DL Smit, W de Ronde - Frontiers in Endocrinology, 2022 - frontiersin.org
Anabolic–androgenic steroids (AAS) are a class of hormones that are widely abused for
their muscle-building and strength-increasing properties in high, nontherapeutic, dosages …

Anabolic androgenic steroids and cardiomyopathy: an update

K Fadah, G Gopi, A Lingireddy, V Blumer… - Frontiers in …, 2023 - frontiersin.org
Anabolic androgenic steroids (AAS) include endogenously produced androgens like
testosterone and their synthetic derivatives. Their influence on multiple metabolic pathways …

Severe biventricular cardiomyopathy in both current and former long-term users of anabolic–androgenic steroids

R Abdullah, A Bjørnebekk, LE Hauger… - European Journal of …, 2024 - academic.oup.com
Aims This study aims to explore the cardiovascular effects of long-term anabolic–androgenic
steroid (AAS) use in both current and former weightlifting AAS users and estimate the …

Premature death in bodybuilders: what do we know?

JM Smoliga, ZT Wilber, BT Robinson - Sports Medicine, 2023 - Springer
Premature deaths in bodybuilders regularly make headlines and are cited as evidence that
bodybuilding is a dangerous activity. A wealth of research has revealed elite athletes …

Health effects of androgen abuse: a review of the HAARLEM study

DL Smit, P Bond, W de Ronde - Current Opinion in Endocrinology …, 2022 - journals.lww.com
It is beyond dispute that androgen abuse is harmful and much of the short-term toxicity is
well documented. To prevent the long-term health hazards, there should be ample focus on …

Persistently decreased quality of life and its determinants in previous illicit androgen users

Y Bulut, N Brandt-Jacobsen, L Buhl… - The Journal of …, 2024 - academic.oup.com
Abstract Background and Objectives Quality of life (QoL) has never been assessed in
previous illicit users of androgens years following androgen cessation. Therefore, the …

[HTML][HTML] Sex-specific cytotoxicity of ostarine in cardiomyocytes

N Leciejewska, E Pruszyńska–Oszmałek… - Molecular and Cellular …, 2023 - Elsevier
Ostarine is the most popular compound in the selective androgen receptor modulator group
(SARMs). Ostarine is used as a physical performance-enhancing agent. The abuse of this …

[PDF][PDF] Abuse of anabolic-androgenic steroids and adverse effects on human organ health: a review

N Ayubi, NW Kusnanik, L Herawati… - Biointerface Res Appl …, 2023 - researchgate.net
Anabolic-androgenic steroids (AAS) are large groups of molecules structurally and
functionally similar to the male hormone testosterone. The use of AAS is well known and …

The impact of image and performance enhancing drugs on atrial structure and function in resistance trained individuals

F Place, H Carpenter, BN Morrison, N Chester… - Echo Research & …, 2023 - Springer
Background Image and performance enhancing drugs (IPEDs) are commonly used in
resistance trained (RT) individuals and negatively impact left ventricular (LV) structure and …

Chronic anabolic androgenic steroid administration reduces global longitudinal strain among off-cycle bodybuilders

S Hammoud, BJF van den Bemt, A Jaber… - International Journal of …, 2023 - Elsevier
Background Supra-physiologic doses of anabolic androgenic steroids (AAS) lead to multiple
cardiovascular complications. The long-term clinical effect of AAS overuse on cardiac …