Nanomedicine in Alzheimer's disease: amyloid beta targeting strategy

G Tosi, F Pederzoli, D Belletti, MA Vandelli… - Progress in brain …, 2019 - Elsevier
The treatment of Alzheimer's disease (AD) is up to today one of the most unsuccessful
examples of biomedical science. Despite the high number of literature evidences detailing …

Nanoparticle delivery systems for substance use disorder

V Kasina, RJ Mownn, R Bahal, GC Sartor - Neuropsychopharmacology, 2022 - nature.com
Innovative breakthroughs in nanotechnology are having a substantial impact in healthcare,
especially for brain diseases where effective therapeutic delivery systems are desperately …

Application of nanodiagnostics and nanotherapy to CNS diseases

W Zhang, W Wang, DX Yu, Z Xiao, Z He - Nanomedicine, 2018 - Taylor & Francis
Alzheimer's disease, Parkinson's disease and stroke are the most common CNS diseases,
all characterized by progressive cellular dysfunction and death in specific areas of the …

Nanoparticle-and liposome-carried drugs: new strategies for active targeting and drug delivery across blood-brain barrier

M Leonor Pinzon-Daza, I Campia… - Current drug …, 2013 - ingentaconnect.com
The blood-brain barrier (BBB), the unusual microvascular endothelial interface between the
central nervous system (CNS) and the circulatory system, is a major hindrance to drug …

Nanoparticle-mediated growth factor delivery systems: A new way to treat Alzheimer's disease

MA Lauzon, A Daviau, B Marcos, N Faucheux - Journal of Controlled …, 2015 - Elsevier
The number of people diagnosed with Alzheimer's disease (AD) is increasing steadily as the
world population ages, thus creating a huge socio-economic burden. Current treatments …

B3Pdb: an archive of blood–brain barrier-penetrating peptides

V Kumar, S Patiyal, R Kumar, S Sahai, D Kaur… - Brain Structure and …, 2021 - Springer
The blood–brain barrier poses major hurdles in the treatment of brain-related ailments. Over
the past decade, interest in peptides-based therapeutics has thrived a lot because of their …

Gold nanoparticles for photothermally controlled drug release

AR Guerrero, N Hassan, CA Escobar, F Albericio… - …, 2014 - Taylor & Francis
In this article, we describe how nanoparticles work in photothermally triggered drug delivery,
starting with a description of the plasmon resonance and the photothermal effect, and how …

Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays

M Piantino, DH Kang, T Furihata, N Nakatani… - Materials Today Bio, 2022 - Elsevier
The blood-brain barrier (BBB), a selective barrier regulating the active and passive transport
of solutes in the extracellular fluid of the central nervous system, prevents the delivery of …

In vitro screening of nanomedicines through the blood brain barrier: A critical review

J Aparicio-Blanco, C Martín-Sabroso, AI Torres-Suárez - Biomaterials, 2016 - Elsevier
The blood-brain barrier accounts for the high attrition rate of the treatments of most brain
disorders, which therefore remain one of the greatest health-care challenges of the twenty …

Blood–brain barrier peptide shuttles

M Sánchez-Navarro, E Giralt, M Teixidó - Current opinion in chemical …, 2017 - Elsevier
Highlights•Targeting of the BBB is a great opportunity for brain delivery of therapeutics.•BBB
peptide shuttles can target both passive and active transport mechanisms present at the …