The purpose of this study was to simulate the concentration‒time profile, Cmax and area
under the curve (AUC) of serum meropenem (MEPM) when administered in mixed infusions …

Pharmacokinetics (PK) is a field of clinical pharmacology that studies how a drug evolves in
the body after administration. Thanks to mathematical modeling, clinical pharmacology is an …

• Clinical pharmacokinetic/pharmacodynamic (PK/PD) indices define a quantitative
relationship between the drug, the MIC and the probability of clinical effectiveness. 1• PK/PD …

Sepsis is a major health issue in the Australian Indigenous population. Unfortunately, the
high rates of mortality and morbidity caused by sepsis or severe sepsis in this population …

抄録 In order to contribute to antimicrobial stewardship, it is extremely important for
pharmacists to apply PK/PD theory (combination of pharamacokinetics (PK) and …

抄録 抗菌薬使用量調査は薬剤耐性菌の発生や拡大の予兆把握に重要であり, antimicrobial use
density (AUD) や days of therapy (DOT) の指標が使用される. 我々は上記指標に加え …

SD, standard deviation SE, standard error tid,“ter in die” in Latin, that means “three times a
day” Vc, volume of distribution for central compartment VCSF, volume of distribution for CSF …

抄録 Piperacillin (PIPC) の高用量における有用性を検討するため, 2018 年~ 2019
年に富山大学附属病院で分離された 12 菌種の薬剤感受性を測定し, モンテカルロシミュレーション …

抗菌薬メロペネムの小児感染症患者および発熱性好中球減少症患者における 母集団薬物動態解 Page
1 抗菌薬メロペネムの小児感染症患者および発熱性好中球減少症患者における 母集団薬物動態解析の …

抄録 So-called pharmacometrics were used for information creation and decision-making in
the drug development and drug approval process. However, for individualized drug therapy …