The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …

Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …

Numerous pathogens can infect the olfactory tract, yet the pandemic caused by SARS-CoV-
2 has strongly emphasized the importance of the olfactory mucosa as an immune barrier …

Anosmia was identified as a hallmark of COVID-19 early in the pandemic, however, with the
emergence of variants of concern, the clinical profile induced by SARS-CoV-2 infection has …

During the first waves of the coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, olfactory …

The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …

Among the numerous long COVID symptoms, olfactory dysfunction persists in∼ 10% of
patients suffering from SARS-CoV-2 induced anosmia. Among the few potential therapies …

Olfactory receptors (ORs) form the most important chemosensory receptor family responsible
for our sense of smell in the nasal olfactory epithelium. This receptor family belongs to the …

Viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), use
respiratory epithelial cells as an entry point for infection. Within the nasal cavity, the olfactory …

Barrier‐forming olfactory glia cells, termed sustentacular cells, play important roles for
immune defense of the olfactory mucosa, for example as entry sites for SARS‐CoV‐2 and …