Reperfusion injury presents a significant obstacle to neuronal survival following successful
recanalization in ischemic stroke, which is characterized by intricate pathophysiological …

Vascular dementia (VaD) constitutes the second most prevalent cause of dementia in the
world after Alzheimer's disease (AD). VaD regroups heterogeneous neurological conditions …

Background: The aim of this study was to evaluate the prognostic role of neutrophil–
lymphocyte ratio (NLR) in patients with acute ischemic stroke (AIS). Methods: PubMed …

Ischemic brain injury causes a local inflammatory response, involving the activation of
resident brain cells such as microglia and the recruitment of infiltrating immune cells …

Microglia are the resident immune cells of the central nervous system that guarantee
immune surveillance and exert also a modulating role on neuronal synaptic development …

Background and Purpose Systemic immune-inflammation index (SII), a novel inflammation
index derived from counts of circulating platelets, neutrophils and lymphocytes, has been …

The brain is both the orchestrator as well as the target of the innate immune system's
response to the aseptic trauma of surgery. When trauma-induced inflammation is not …

Background Glia-mediated neuroinflammation is related to brain injury exacerbation after
cerebral ischemia/reperfusion (I/R) injury. Astrocytic hemichannels or gap junctions, which …

Ischemic stroke is a leading cause of morbidity and mortality and disproportionally affects
women, in part due to their higher longevity. Older women have poorer outcomes after …

Increasing evidences have demonstrated that inflammation is involved in the mechanisms of
acute ischemic stroke (AIS). As an important and easy-to-measure inflammatory marker …