Platelet-to-neutrophil ratio is a prognostic marker for 90-days outcome in acute ischemic stroke

PP Jin, XM Li, J Chen, ZR Zhang, WW Hu… - Journal of Clinical …, 2019 - Elsevier
To investigate the prognostic value of platelet-to-neutrophil ratio (PNR) in acute ischemic
stroke (AIS) patients. In this study, a total of 400 AIS patients were included. Demographic …

CircUSP36 attenuates ischemic stroke injury through the miR-139-3p/SMAD3/Bcl2 signal axis

J Yang, W He, L Gu, J Long, L Zhu, R Zhang… - Clinical …, 2022 - portlandpress.com
Circular RNAs (circRNAs) play important roles in a variety of physiological and pathological
processes. Researches demonstrated that circRNAs provided novel strategies for the …

Immune cells after ischemic stroke onset: roles, migration, and target intervention

L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …

Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke

P Carmona-Mora, BP Ander… - Journal of Cerebral …, 2021 - journals.sagepub.com
Understanding cell-specific transcriptome responses following intracerebral hemorrhage
(ICH) and ischemic stroke (IS) will improve knowledge of the immune response to brain …

Prognostic value of the systemic inflammation response index in patients with acute ischemic stroke

Y Zhou, Y Zhang, M Cui, Y Zhang… - Brain and behavior, 2022 - Wiley Online Library
Objectives Inflammation plays an essential role in acute ischemic stroke (AIS). Recent
studies have recognized the systemic inflammation response index (SIRI) as a useful index …

The pericyte–glia interface at the blood–brain barrier

P Giannoni, J Badaut, C Dargazanli… - Clinical …, 2018 - portlandpress.com
The cerebrovasculature is a multicellular structure with varying rheological and permeability
properties. The outer wall of the brain capillary endothelium is enclosed by pericytes and …

A novel small-molecular CCR5 antagonist promotes neural repair after stroke

Q Wu, L Cui, W Ma, S Wang, Z Zhang, Z Feng… - Acta Pharmacologica …, 2023 - nature.com
Abstract Chemokine receptor 5 (CCR5) is one of the main co-receptors of HIV-1, and has
been found to be a potential therapeutic target for stroke. Maraviroc is a classic CCR5 …

[HTML][HTML] Vinpocetine protects against cerebral ischemia-reperfusion injury by targeting astrocytic connexin43 via the PI3K/AKT signaling pathway

M Zhao, S Hou, L Feng, P Shen, D Nan… - Frontiers in …, 2020 - frontiersin.org
Vinpocetine (Vinp) is known for its neuroprotective properties. However, the protective
mechanism of Vinp against cerebral ischemia/reperfusion (I/R) injury should be further …

Controlling nutritional status score for predicting 3-mo functional outcome in acute ischemic stroke

H Naito, T Nezu, N Hosomi, S Aoki, N Kinoshita, J Kuga… - Nutrition, 2018 - Elsevier
Background Malnutrition is an independent risk factor for poor outcomes in patients with
acute ischemic stroke. However, the indicator of malnutrition has not yet been established …

Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke

R Hao, X Qi, X Xia, L Wang, X Li - Journal of Clinical Laboratory …, 2022 - Wiley Online Library
Purpose Malnutrition, as determined by the Controlling Nutritional Status (CONUT), has an
effect on the 3‐month and long‐term prognosis of stroke patients. The association between …