[HTML][HTML] Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease

A García-Lafuente, E Guillamón, A Villares… - Inflammation …, 2009 - Springer
Chronic inflammation is being shown to be increasingly involved in the onset and
development of several pathological disturbances such as arteriosclerosis, obesity …

Edible mushrooms: role in the prevention of cardiovascular diseases

E Guillamón, A García-Lafuente, M Lozano… - Fitoterapia, 2010 - Elsevier
Edible mushrooms are a valuable source of nutrients and bioactive compounds in addition
to a growing appeal for humans by their flavors and culinary features. Recently, they have …

Inflammation: a novel therapeutic target/direction in atherosclerosis

B Li, W Li, X Li, H Zhou - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …

Is hypertension an inflammatory process?

CJ Boos, GYH Lip - Current pharmaceutical design, 2006 - ingentaconnect.com
The risk factors for hypertension are only partly known, and accounts for the some of the
deficiencies in current primary prevention strategies and in the design of new drugs for the …

NF-κB signaling at the crossroads of inflammation and atherogenesis: searching for new therapeutic links

I Pateras, C Giaginis, C Tsigris, E Patsouris… - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: NF-κB is a protein complex acting as a primary transcription factor and fast
messenger to harmful cellular stimuli, including inflammation. Carotid atherosclerosis is an …

The role of an experimental model of atherosclerosis: apoE-knockout mice in developing new drugs against atherogenesis

J Jawien - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
Although atherosclerosis was previously thought to be mainly a degenerative disease, it is
now well ascertained that its pathogenesis is inflammatory. There was a pivotal role of apoE …

A review of high-dose statin therapy: targeting cholesterol and inflammation in atherosclerosis

TN Patel, MH Shishehbor, DL Bhatt - European heart journal, 2007 - academic.oup.com
Abstract Lipid lowering with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or
'statins' has dramatically reduced morbidity and mortality in patients with established …

[HTML][HTML] Role of lipid-lowering therapy in peripheral artery disease

AD Belur, AJ Shah, SS Virani, M Vorla… - Journal of Clinical …, 2022 - mdpi.com
Atherosclerosis is a multifactorial, lipoprotein-driven condition that leads to plaque formation
within the arterial tree, leading to subsequent arterial stenosis and thrombosis that accounts …

[HTML][HTML] Identification of differently expressed mRNAs in atherosclerosis reveals CDK6 Is regulated by circHIPK3/miR-637 axis and promotes cell growth in human …

L Kang, H Jia, B Huang, S Lu, Z Chen, J Shen… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is the leading cause of heart disease and stroke, and one of the leading
causes of death and disability worldwide. The phenotypic transformation of vascular smooth …