During the past 10 years, preclinical studies implicating sustained androgen receptor (AR)
signalling as the primary driver of castration-resistant prostate cancer (CRPC) have led to …

The normal prostate and early-stage prostate cancers depend on androgens for growth and
survival, and androgen ablation therapy causes them to regress. Cancers that are not cured …

The lack of in vitro prostate cancer models that recapitulate the diversity of human prostate
cancer has hampered progress in understanding disease pathogenesis and therapy …

In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs;
however, pathological fractures frequently occur in PCa patients, and bone resorption is …

New incidence of prostate cancer is a major public health issue in the Western world, and
has been rising in other areas of the globe in recent years. In an effort to understanding the …

BACKGROUND This study presents a comprehensive survey and characterization of
available prostate carcinoma cell lines, most of which have been widely used but are …

Metastasis to bone is common in lung, kidney, breast and prostate cancers. However,
prostate cancer is unique in that bone is often the only clinically detectable site of …

The androgen receptor (AR) is involved in the development, growth and progression of
prostate cancer 1 (CaP). CaP often progresses from an androgen-dependent to an …

PURPOSE:: This is part 1 of a 2-part review. Research into the molecular mechanisms
underlying the various aspects of prostate cancer (PCa) requires the use of in vivo and in …

Three cholangiocarcinoma (CCA) cell line—formerly named, M156, M213 and M214 have
been intensively used with discrepancy of their tumor origins. They were assumed to be …