A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical Microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

[HTML][HTML] Comprehensive review on Alzheimer's disease: causes and treatment

Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a disorder that causes degeneration of the cells in the brain and
it is the main cause of dementia, which is characterized by a decline in thinking and …

[HTML][HTML] Long-term respiratory and neurological sequelae of COVID-19

F Wang, RM Kream, GB Stefano - Medical science monitor …, 2020 - ncbi.nlm.nih.gov
Since the initial reports of coronavirus disease 2019 (COVID-19) in China in late 2019,
infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have …

[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

[HTML][HTML] Alzheimer's disease: an updated overview of its genetics

J Andrade-Guerrero, A Santiago-Balmaseda… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

[HTML][HTML] The gut microbiome alterations and inflammation-driven pathogenesis of Alzheimer's disease—a critical review

M Sochocka, K Donskow-Łysoniewska, BS Diniz… - Molecular …, 2019 - Springer
One of the most important scientific discoveries of recent years was the disclosure that the
intestinal microflora takes part in bidirectional communication between the gut and the brain …

[HTML][HTML] Melatonin regulates Aβ production/clearance balance and Aβ neurotoxicity: A potential therapeutic molecule for Alzheimer's disease

Y Li, J Zhang, J Wan, A Liu, J Sun - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disease with multiple
predisposing factors and complicated pathogenesis. Aβ peptide is one of the most important …

Cathepsin B gene knockout improves behavioral deficits and reduces pathology in models of neurologic disorders

G Hook, T Reinheckel, J Ni, Z Wu, M Kindy… - Pharmacological …, 2022 - ASPET
Cathepsin B (CTSB) is a powerful lysosomal protease. This review evaluated CTSB gene
knockout (KO) outcomes for amelioration of brain dysfunctions in neurologic diseases and …

[HTML][HTML] Chronic endometritis and altered embryo implantation: a unified pathophysiological theory from a literature systematic review

G Buzzaccarini, A Vitagliano, A Andrisani… - Journal of Assisted …, 2020 - Springer
Purpose Chronic endometritis (CE) is a frequent hysteroscopic and histological finding
which affects embryo transfer implantation during IVF-ICSI cycles. In particular, CE impairs …

[HTML][HTML] The role of periodontitis and periodontal bacteria in the onset and progression of Alzheimer's disease: a systematic review

M Dioguardi, V Crincoli, L Laino, M Alovisi… - Journal of clinical …, 2020 - mdpi.com
The evidence of a connection between the peripheral inflammatory processes and
neurodegenerative diseases of the central nervous system is becoming more apparent. This …