[HTML][HTML] The landscape of implantation and placentation: deciphering the function of dynamic RNA methylation at the maternal-fetal interface

S Wu, H Xie, Y Su, X Jia, Y Mi, Y Jia… - Frontiers in …, 2023 - frontiersin.org
The maternal-fetal interface is defined as the interface between maternal tissue and sections
of the fetus in close contact. RNA methylation modifications are the most frequent kind of …

[HTML][HTML] Associations between obesity, smoking behaviors, reproductive traits and spontaneous abortion: a univariable and multivariable Mendelian randomization …

Q Wang, F Liu, Y Tuo, L Ma, X Feng - Frontiers in Endocrinology, 2023 - frontiersin.org
Background The correlation between potential risk factors such as obesity (leg fat
percentage (left), arm fat percentage (left), waist circumference, body fat percentage, trunk …

[HTML][HTML] N6-methyladenosine modifications in maternal-fetal crosstalk and gestational diseases

S Wu, K Liu, B Zhou, S Wu - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
As a medium among pregnant women, environment and fetus, placenta owns powerful and
delicate epigenetic processes to regulate gene expression and maintain cellular …

The Role of N6-methyladenosine Modification in Gametogenesis and Embryogenesis: Impact on Fertility

Y Wang, C Yang, H Sun, H Jiang… - Genomics …, 2024 - academic.oup.com
The most common epigenetic modification of messenger ribonucleic acids (mRNAs) is N 6-
methyladenosine (m6A), which is mainly located near the 3'untranslated region of mRNAs …

Exploring the role of m6A modification in the great obstetrical syndromes

J Ning, J Yan, H Yang - The Journal of Maternal-Fetal & Neonatal …, 2023 - Taylor & Francis
Abstract Background N6-methyladenosine (m6A) is one of the predominant RNA epigenetic
modifications that modify RNAs reversibly and dynamically by “writers”(methyltransferase),“ …

[HTML][HTML] Regulatory role of m6A epitranscriptomic modifications in normal development and congenital malformations during embryogenesis

Y Yao, P Liu, Y Li, W Wang, H Jia, Y Bai, Z Yuan… - Biomedicine & …, 2024 - Elsevier
The discovery of N6-methyladenosine (m 6 A) methylation and its role in translation has led
to the emergence of a new field of research. Despite accumulating evidence suggesting that …

[HTML][HTML] Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus

J Ning, J Yan, S Wang, Z Cui, Y Xue, J Juan, H Yang - iScience, 2024 - cell.com
Type 2 diabetes mellitus (T2DM) represents a common complication during pregnancy that
affects fetoplacental development. We demonstrated the existence of impaired trophoblast …

[HTML][HTML] Differential proteomics of placentas reveals metabolic disturbance and oxidative damage participate yak spontaneous miscarriage during late pregnancy

J Pei, S Zhao, M Yin, F Wu, J Li, G Zhang, X Wu… - BMC Veterinary …, 2022 - Springer
Background High spontaneous miscarriage rate in yak, especially during late pregnancy,
have caused a great economic loss to herdsmen living in the Qinghai-Tibet plateau …

The N6-methyladenosine modification in pathologic angiogenesis

B Li, H Xuan, Y Yin, S Wu, L Du - Life Sciences, 2024 - Elsevier
The vascular system is a vital circulatory network in the human body that plays a critical role
in almost all physiological processes. The production of blood vessels in the body is a …

FTO promotes gefitinib-resistance by enhancing PELI3 expression and autophagy in non-small cell lung cancer

YZ He, XN Li, HT Li, XH Bai, YC Liu, FN Li, BL Lv… - Pulmonary …, 2024 - Elsevier
The established recognition of N6-methyladenosine (m6A) modification as an indispensable
regulatory agent in human cancer is widely accepted. However, the understanding of m6A's …