A road map for understanding molecular and genetic determinants of osteoporosis
Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density …
[HTML][HTML] Role of dietary supplements and probiotics in modulating microbiota and bone health: the gut-bone axis
Osteoporosis is characterized by an alteration of bone microstructure with a decreased bone
mineral density, leading to the incidence of fragility fractures. Around 200 million people are …
mineral density, leading to the incidence of fragility fractures. Around 200 million people are …
The association of gut microbiota with osteoporosis is mediated by amino acid metabolism: multiomics in a large cohort
Context Several small studies have suggested that the gut microbiome might influence
osteoporosis, but there is little evidence from human metabolomics studies to explain this …
osteoporosis, but there is little evidence from human metabolomics studies to explain this …
[HTML][HTML] Exercise for osteoporosis: a literature review of pathology and mechanism
L Zhang, YL Zheng, R Wang, XQ Wang… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis (OP) is a disease that weakens bones and has a high morbidity rate
worldwide, which is prevalent among the elderly, particularly, women of postmenopausal …
worldwide, which is prevalent among the elderly, particularly, women of postmenopausal …
Osteosarcopenia: A case of geroscience
Many older persons lose their mobility and independence due to multiple diseases
occurring simultaneously. Geroscience is aimed at developing innovative approaches to …
occurring simultaneously. Geroscience is aimed at developing innovative approaches to …
[HTML][HTML] ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss
W Yang, HY Li, YF Wu, RJ Mi, WZ Liu, X Shen… - … Therapy-Nucleic Acids, 2021 - cell.com
N-acetyltransferase 10 (NAT10) is the key enzyme for N4-acetylcytidine (ac4C) modification
of mRNA, which participates in various cellular processes and is related to many diseases …
of mRNA, which participates in various cellular processes and is related to many diseases …
[HTML][HTML] Nrf2 epigenetic derepression induced by running exercise protects against osteoporosis
X Chen, X Zhu, A Wei, F Chen, Q Gao, K Lu, Q Jiang… - Bone research, 2021 - nature.com
Osteoporosis (OP) is a common skeletal disease involving low bone mineral density (BMD)
that often leads to fragility fracture, and its development is affected by multiple cellular …
that often leads to fragility fracture, and its development is affected by multiple cellular …
[HTML][HTML] Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics
YJ Chen, WA Chang, MS Huang, CH Chen, KY Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
During the aging process, impaired osteoblastic function is one key factor of imbalanced
bone formation and age-related bone loss. The aim of this study is to explore the …
bone formation and age-related bone loss. The aim of this study is to explore the …
[HTML][HTML] Regulatory Role of RNA N6-Methyladenosine Modification in Bone Biology and Osteoporosis
X Chen, W Hua, X Huang, Y Chen, J Zhang… - Frontiers in …, 2020 - frontiersin.org
Osteoporosis is a metabolic skeletal disorder in which bone mass is depleted and bone
structure is destroyed to the degree that bone becomes fragile and prone to fractures …
structure is destroyed to the degree that bone becomes fragile and prone to fractures …
[HTML][HTML] Prospect of stem cell therapy and regenerative medicine in osteoporosis
The field of cell therapy and regenerative medicine can hold the promise of restoring normal
tissues structure and function. Additionally, the main targets of stem cell-based therapies are …
tissues structure and function. Additionally, the main targets of stem cell-based therapies are …