Maternal passage of immunoglobulin G (IgG) is an important passive mechanism for
protecting the infant while the neonatal immune system is still immature and ineffective. IgG …

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by immune-
mediated injury of exocrine glands. Extensive lymphocytic infiltrates may contribute to the …

Fetal arrhythmias are mostly benign and transient. However, some of them are associated
with structural defects or can cause heart failure, fetal hydrops, and can lead to intrauterine …

Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …

Background There is a high prevalence of autoimmune conditions in women specially in the
reproductive years; thus, the association with adverse pregnancy outcomes has been widely …

Background: Neonatal lupus (NL) is a clinical syndrome that develops in the fetus as a result
of maternal autoimmune antibodies. Congenital complete heart block (CHB) is the most …

In autoimmune rheumatic diseases, immune hyperactivity and chronic inflammation
associate with immune dysregulation and the breakdown of immune self-tolerance. A …

This chapter first explains the incidence or prevalence of congenital anomalies or genetic
disorders. Many factors influence efforts to accurately determine the incidence or prevalence …

ABSTRACT Anti‐Ro/SSA‐antibody‐mediated endocardial fibroelastosis (EFE) without
atrioventricular (AV) block at presentation is a rare cardiac phenotype. We report on 11 …

Background and aims Emerging evidence suggests an arrhythmogenic effect of Anti-
Ro/SSA (anti-Ro) and anti-La/SSB (anti-La) antibodies in adults, potentially involving a …