Applications of focused ultrasound in the brain: from thermoablation to drug delivery

Y Meng, K Hynynen, N Lipsman - Nature Reviews Neurology, 2021 - nature.com
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

[HTML][HTML] High intensity focused ultrasound: The fundamentals, clinical applications and research trends

IAS Elhelf, H Albahar, U Shah, A Oto… - Diagnostic and …, 2018 - Elsevier
Diagnostic ultrasound has been clinically used for decades. More recently, high intensity
focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive …

Emerging ultrasonic bioelectronics for personalized healthcare

L Jiang, J Wu - Progress in Materials Science, 2023 - Elsevier
Emerging ultrasonic bioelectronics (UBEs) with wearable, implantable or highly integrated
forms enable continuous health monitoring and on-demand medical therapy at the point of …

[HTML][HTML] Ultrasonic modulation of neural circuit activity

WJ Tyler, SW Lani, GM Hwang - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Low-intensity ultrasound can non-invasively modulate neuronal
activity.•Ultrasound can modulate brain circuits at high spatial resolutions.•Neuromodulation …

[HTML][HTML] Focused ultrasound for neuromodulation

DP Darrow - Neurotherapeutics, 2019 - Elsevier
For more than 70 years, the promise of noninvasive neuromodulation using focused
ultrasound has been growing while diagnostic ultrasound established itself as a foundation …

Acoustically targeted chemogenetics for the non-invasive control of neural circuits

JO Szablowski, A Lee-Gosselin, B Lue… - Nature biomedical …, 2018 - nature.com
Neurological and psychiatric disorders are often characterized by dysfunctional neural
circuits in specific regions of the brain. Existing treatment strategies, including the use of …

Transcranial focused ultrasound: a new tool for non-invasive neuromodulation

M Fini, WJ Tyler - International Review of Psychiatry, 2017 - Taylor & Francis
Ultrasound (US) is widely known for its utility as a biomedical imaging modality. An
abundance of evidence has recently accumulated showing that US is also useful for non …

Ultrasound for the brain: a review of physical and engineering principles, and clinical applications

W Qiu, A Bouakaz, EE Konofagou… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
The emergence of new ultrasound technologies has improved our understanding of the
brain functions and offered new opportunities for the treatment of brain diseases. Ultrasound …

[HTML][HTML] Transcranial focused ultrasound stimulation of cortical and thalamic somatosensory areas in human

HC Kim, W Lee, DS Weisholtz, SS Yoo - PLoS One, 2023 - journals.plos.org
The effects of transcranial focused ultrasound (FUS) stimulation of the primary
somatosensory cortex and its thalamic projection (ie, ventral posterolateral nucleus) on the …

[HTML][HTML] Noninvasive brain stimulation for neurorehabilitation in post-stroke patients

KP Li, JJ Wu, ZL Zhou, DS Xu, MX Zheng, XY Hua… - Brain Sciences, 2023 - mdpi.com
Characterized by high morbidity, mortality, and disability, stroke usually causes symptoms of
cerebral hypoxia due to a sudden blockage or rupture of brain vessels, and it seriously …