Over 20 years ago, it was first proposed that autoinflammation underpins a handful of rare
monogenic disorders characterized by recurrent fever and systemic inflammation. The …

Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

Purpose The aims of this article were to systematically review the literature about the
mechanism of action of colchicine in the multimodal pathology of acute inflammation …

In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

Nanoparticles (NPs) are materials with overall dimensions in the nanoscale range. They
have unique physicochemical properties, and have emerged as important players in current …

Kinesins are a family of molecular motors that use the energy of ATP hydrolysis to move
along the surface of, or destabilize, microtubule filaments. Much progress has been made in …

Life emerges from thousands of biochemical processes occurring within a shared
intracellular environment. We have gained deep insights from in vitro reconstitution of …

Neuronal homeostasis depends on the proper functioning of different quality control
systems. All intracellular components are subjected to continuous turnover through the …

This article provides an overview of principles and barriers relevant to intracellular drug and
gene transport, accumulation and retention (collectively called as drug delivery) by means of …

Active transport along the axon is crucial to the neuron. Motor-driven transport supplies the
distal synapse with newly synthesized proteins and lipids, and clears damaged or misfolded …