Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …

Westernized populations are plagued by a plethora of chronic non-infectious degenerative
diseases, termed as “civilization diseases”, like obesity, diabetes, cardiovascular diseases …

Diabetes mellitus is one of the major public health problems worldwide. Considerable recent
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …

Globally, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD)
epidemics is increasing rapidly and has huge financial and emotional costs. The purpose of …

The endoplasmic reticulum (ER) acts as a moving organelle with many important cellular
functions. As the ER lacks sufficient nutrients under pathological conditions leading to …

Metabolic syndrome is co-occurrence of obesity, insulin resistance, atherogenic
dyslipidemia (high triglyceride, low high density lipoprotein cholesterol), and hypertension. It …

Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …