Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

A transparent cornea is essential for the formation of a clear image on the retina. The human
cornea is arranged into well-organized layers, and each layer plays a significant role in …

The corneal endothelium is responsible for maintaining the hydration of the cornea. This is
through a “Pump-Leak” mechanism where the active transport properties of the endothelium …

Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv FE Nilsson, James Ver Hoeve, and
Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye …

The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

The corneas of all animal species remain transparent because of the epithelial barrier, the
stromal latticelike arrangement of the collagen fibrils, and the endothelial cells. Depending …

Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in
the elderly. Since the first description of an association between FECD and common …

Due to its localization and function, the cornea is regularly exposed to sunlight and
atmospheric oxygen, mainly dioxygen, which produce reactive oxygen species (ROS) …

The main treatment available for restoration of the corneal endothelium is keratoplasty. This
procedure is faced with several difficulties, including the shortage of donor tissue, post …