[HTML][HTML] Oxidative stress in the eye and its role in the pathophysiology of ocular diseases
EW Böhm, F Buonfiglio, AM Voigt, P Bachmann, T Safi… - Redox Biology, 2023 - Elsevier
Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …
Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …
endothelial dystrophy and the leading indication for corneal transplantation worldwide …
Corneal endothelial cell dysfunction: etiologies and management
S Feizi - Therapeutic advances in ophthalmology, 2018 - journals.sagepub.com
A transparent cornea is essential for the formation of a clear image on the retina. The human
cornea is arranged into well-organized layers, and each layer plays a significant role in …
cornea is arranged into well-organized layers, and each layer plays a significant role in …
Molecular mechanisms underlying the corneal endothelial pump
JA Bonanno - Experimental eye research, 2012 - Elsevier
The corneal endothelium is responsible for maintaining the hydration of the cornea. This is
through a “Pump-Leak” mechanism where the active transport properties of the endothelium …
through a “Pump-Leak” mechanism where the active transport properties of the endothelium …
[图书][B] Adler's Physiology of the Eye: Expert Consult-Online and Print
LA Levin, SFE Nilsson, J Ver Hoeve, S Wu… - 2011 - books.google.com
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv FE Nilsson, James Ver Hoeve, and
Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye …
Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye …
[HTML][HTML] Approaches for corneal endothelium regenerative medicine
The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …
Advances in the reproducibility and accessibility of surgical techniques are increasing the …
[HTML][HTML] The balance between corneal transparency and edema the proctor lecture
HF Edelhauser - Investigative ophthalmology & visual science, 2006 - tvst.arvojournals.org
The corneas of all animal species remain transparent because of the epithelial barrier, the
stromal latticelike arrangement of the collagen fibrils, and the endothelial cells. Depending …
stromal latticelike arrangement of the collagen fibrils, and the endothelial cells. Depending …
[HTML][HTML] TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease
MP Fautsch, ED Wieben, KH Baratz… - Progress in retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in
the elderly. Since the first description of an association between FECD and common …
the elderly. Since the first description of an association between FECD and common …
Oxidative stress in the pathogenesis of keratoconus and Fuchs endothelial corneal dystrophy
KA Wojcik, A Kaminska, J Blasiak, J Szaflik… - International journal of …, 2013 - mdpi.com
Due to its localization and function, the cornea is regularly exposed to sunlight and
atmospheric oxygen, mainly dioxygen, which produce reactive oxygen species (ROS) …
atmospheric oxygen, mainly dioxygen, which produce reactive oxygen species (ROS) …
Corneal endothelium: developmental strategies for regeneration
J Zavala, GR Lopez Jaime, CA Rodriguez Barrientos… - Eye, 2013 - nature.com
The main treatment available for restoration of the corneal endothelium is keratoplasty. This
procedure is faced with several difficulties, including the shortage of donor tissue, post …
procedure is faced with several difficulties, including the shortage of donor tissue, post …