Comorbidities and the impact of atopic dermatitis

JI Silverberg - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with
substantial patient and population burdens. A number of comorbid health problems occur in …

The role of environmental exposures in atopic dermatitis

S Narla, JI Silverberg - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review Although genetic factors clearly play a role in the development
of atopic dermatitis (AD), the recent dramatic increase in the prevalence of AD in low-and …

Zinc and atopic dermatitis: a systematic review and meta‐analysis

NA Gray, A Dhana, DJ Stein… - Journal of the European …, 2019 - Wiley Online Library
Zinc plays a central role in skin integrity via barrier and immune mechanisms and may also
be relevant in the pathogenesis of atopic dermatitis (AD). However, little is known about the …

IBT-V02: A Multicomponent Toxoid Vaccine Protects Against Primary and Secondary Skin Infections Caused by Staphylococcus aureus

H Karauzum, A Venkatasubramaniam… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus causes a wide range of diseases from skin infections to life
threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site …

The Role of Immune Defects and Colonization of Staphylococcus aureus in the Pathogenesis of Atopic Dermatitis

D Nowicka, E Grywalska - Analytical Cellular Pathology, 2018 - Wiley Online Library
Atopic dermatitis (AD) is a condition with a complex and not fully understood etiology. In
patients with AD, acute skin lesions are colonized by a greater number of Staphylococcus …

Role of superantigens in allergic inflammation: their relationship to allergic rhinitis, chronic rhinosinusitis, asthma, and atopic dermatitis

NB Muluk, F Altın, C Cingi - American Journal of Rhinology & …, 2018 - journals.sagepub.com
Objectives Our intention was to review all material published to date regarding
superantigens (SAgs) and allergy from an otorhinolaryngological viewpoint to understand …

Enterotoxin Gene Cluster and selX Are Associated with Atopic Dermatitis Severity—A Cross-Sectional Molecular Study of Staphylococcus aureus Superantigens

L Blicharz, M Żochowski, K Szymanek-Majchrzak… - Cells, 2022 - mdpi.com
Staphylococcus aureus superantigens (SAgs) have been reported to aggravate atopic
dermatitis. However, comprehensive analyses of these molecules in multiple microniches …

[HTML][HTML] The quest for bacterial allergens

M Nordengrün, S Michalik, U Völker, BM Bröker… - International Journal of …, 2018 - Elsevier
Allergies are complex diseases featuring local tissue inflammation, which is characterized
by an exaggerated type 2 immune response to environmental compounds known as …

Host-microbe interaction on the skin and its role in the pathogenesis and treatment of atopic dermatitis

D Nowicka, K Chilicka, I Dzieńdziora-Urbińska - Pathogens, 2022 - mdpi.com
Atopic dermatitis (AD) is a condition with a complex and unclear aetiology. Possible causes
of AD encompass alterations in the structure and function of the epidermal barrier …

Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis

V Kopfnagel, S Dreyer, J Zeitvogel, DH Pieper, A Buch… - Allergy, 2021 - Wiley Online Library
Background The high susceptibility of AD patients to microbial skin infections has been
attributed to a deficient antimicrobial peptide (AMP) expression, which is contradicted by a …