In vitro production (IVP) of embryos and associated technologies in cattle have shown
significant progress in recent years, in part driven by a better understanding of the full …

Only a fraction of oocytes present in the ovaries at birth are ever ovulated during the lifetime
of a female mammal. In vitro maturation (IVM) offers the possibility to exploit what is a largely …

The ovarian follicle provides the oocyte with the ideal environment for growth and
development in preparation for ovulation and fertilisation. The follicle undergoes many …

Endometriosis, a highly prevalent gynecological disease, is often associated with infertility,
even in its milder forms (minimal and mild endometriosis). However, no consensus has been …

In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …

Reduced oocyte and embryo quality are recognised as major factors in the problem of
disappointing fertility in high producing dairy cows. This review aims to shed more light on …

Background The maturation and successful acquisition of developmental competence by an
oocyte, the female gamete, during folliculogenesis is highly dependent on molecular …

The follicle is a unique micro-environment within which the oocyte can develop and mature
to a fertilisable gamete. The aim of this study was to investigate the ability of a panel of …

The bi-directional communication between the oocyte and its companion cumulus cells
(CCs) is crucial for development and functions of both cell types. Transcripts that are …

Extracellular vesicles (EVs) are nanoparticles secreted by ovarian follicle cells. Extracellular
vesicles are an important form of intercellular communication, since they carry bioactive …