For many years, stem cell metabolism was viewed as a byproduct of cell fate status rather
than an active regulatory mechanism; however, there is now a growing appreciation that …

This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

The mouse embryo undergoes compaction at the 8-cell stage, and its transition to 16 cells
generates polarity such that the outer apical cells are trophectoderm (TE) precursors and the …

Recent studies link changes in energy metabolism with the fate of pluripotent stem cells
(PSC s). Safe use of PSC derivatives in regenerative medicine requires an enhanced …

Oxygen consumption of preimplantation and early postimplantation mouse embryos has
been measured using a novel noninvasive ultramicrofluorescence technique, based on an …

This study was an investigation of metabolism during bovine preimplantation development
from the oocyte up to the hatched blastocyst derived in vitro or in vivo. Metabolism was …

With the growing move in in-vitro fertilization (IVF) clinics to transfer fewer embryos to
women, there is an increasing reliance on the IVF laboratory to maximize embryo viability …

Mammalian pre-implantation development culminates in the formation of the blastocyst
consisting of two distinct cell lineages, approximately a third of the cells comprise the …

The purpose of this study was to determine the effect of heparin-binding epidermal growth
factor (HB-EGF) on human embryo development in vitro from days 2 to 14 post-insemination …

Glucose utilization was studied in preimplantation embryos from normal and diabetic mice.
With use of ultramicrofluorometric enzyme assays, intraembryonic free glucose in single …